A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids

A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids Publisher Pubmed

Moghaddam AZ¹ ; Bameri AE¹ ; Ganjali MR^{2, 3} ; Alexovic M⁴ ; Jazi ME⁵ ; Tabani H⁶

Show Affiliations

1. Department of Chemistry, Faculty of Science, University of Birjand, Birjand, Iran
2. Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran
3. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Medical and Clinical Biophysics, Faculty of Medicine, University of P.J. Safarik in Kosice, Kosice, SK-04011, Slovakia
5. Department of Chemistry, Mississippi State University, Mississippi State, Mississippi, 39762, MS, United States
6. Department of Environmental Geology, Research Institute of Applied Sciences (ACECR), Shahid Beheshti University, Tehran, Iran

Source: Bioanalysis Published:2021

Abstract

Aim: Hollow-fiber-based supported liquid membrane was modified utilizing nanostructures such as graphite, graphene oxide or nitrogen-doped graphene oxide, for electro-membrane extraction (EME) of imatinib and sunitinib from biological fluids. By applying these conductive nanostructures, a low-voltage EME device (6.0 V) was fabricated. Materials & methods: A response surface methodology through central composite design was used to evaluate and optimize effects of various essential factors that influence on normalized recovery. Results: Optimal extraction conditions were set as, 1-octanol with 0.01 % (w/v) graphene oxide functioning as the supported liquid membrane, an extraction time of 17.0 min, pH of the acceptor and the donor phase of 2.8 and 7.9, respectively. Conclusion: The method was successfully applied to quantify imatinib and sunitinib in biological fluids. © 2021 Authors

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Style	Citing Format
MLA	Moghaddam AZ, et al.. "A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids." Bioanalysis, vol. 13, no. 18, 2021, pp. 1401-1413.
APA	Moghaddam AZ, Bameri AE, Ganjali MR, Alexovic M, Jazi ME, Tabani H (2021). A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids. Bioanalysis, 13(18), 1401-1413.
Chicago	Moghaddam AZ, Bameri AE, Ganjali MR, Alexovic M, Jazi ME, Tabani H. "A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids." Bioanalysis 13, no. 18 (2021): 1401-1413.
Harvard	Moghaddam AZ et al. (2021) 'A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids', Bioanalysis, 13(18), pp. 1401-1413.
Vancouver	Moghaddam AZ, Bameri AE, Ganjali MR, Alexovic M, Jazi ME, Tabani H. A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids. Bioanalysis. 2021;13(18):1401-1413.
BibTex	@article{ author = {Moghaddam AZ and Bameri AE and Ganjali MR and Alexovic M and Jazi ME and Tabani H}, title = {A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids}, journal = {Bioanalysis}, volume = {13}, number = {18}, pages = {1401-1413}, year = {2021} }
RIS	TY - JOUR AU - Moghaddam AZ AU - Bameri AE AU - Ganjali MR AU - Alexovic M AU - Jazi ME AU - Tabani H TI - A Low-Voltage Electro-Membrane Extraction for Quantification of Imatinib and Sunitinib in Biological Fluids JO - Bioanalysis VL - 13 IS - 18 SP - 1401 EP - 1413 PY - 2021 ER -

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