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Complications of Low Dose Propofol in Electroconvulsive Therapy: A Case Series



Rahmati J1 ; Shahriari A2 ; Khooshideh M3
Authors
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Authors Affiliations
  1. 1. Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Arash Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Anaesthesia# Pain and Intensive Care Published:2019

Abstract

We report a cases series (of four cases) of serious complications observed after propofol injection for electroconvulsive therapy. The signs and symptoms included hyperthermia, hypotension, lethargy, pancytopenia or leukocytosis, as well as renal and hepatic laboratory parameters disturbances. In all of these cases, signs and symptoms improved rapidly. Although propofol used in these patients was drawn from a multi-dose vial, which can be a source of contamination and infection, rapid disappearance of the signs and symptoms in 3 of the patients after three hours, and remission of hypotension and lethargy the fourth patient within 10 hours, precludes the possibility of sepsis. Anesthesiologists must remain vigilant during propofol use and must shun the use of multi-dose vials. © 2019 Faculty of Anaesthesia, Pain and Intensive Care, AFMS. All rights reserved.