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Nuclear Medicine Imaging in Non-Seminomatous Germ Cell Tumors: Lessons Learned From the Past Failures Publisher Pubmed



Ayati N1, 2 ; Askari E3 ; Fotouhi M4 ; Soltanabadi M5 ; Aghaee A3 ; Roustaei H6 ; Scott AM7, 8, 9
Authors
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Authors Affiliations
  1. 1. Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital, Sydney, NSW, Australia
  2. 2. St. Vincent’s Clinical School, University of New South Wales, Sydney, NSW, Australia
  3. 3. Nuclear Medicine Research Center, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran
  4. 4. Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Nuclear Medicine, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria
  7. 7. Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia
  8. 8. School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia
  9. 9. Department of Molecular Imaging & amp
  10. 10. Therapy, Austin Health, 145 Studley Road, Heidelberg, 3084, VIC, Australia
  11. 11. Department of Medicine, University of Melbourne, Melbourne, VIC, Australia

Source: Cancer Imaging Published:2024


Abstract

There is an unmet need for a more accurate molecular imaging radiotracer in the field of non-seminomatous germ cell tumors (NSGCT). The clinical problem is that no single imaging modality is able to differentiate teratoma from necrotic tissue in NSGCTs, which the nuclear medicine techniques are no exception. The exponential growth in the list of potentially promising radiotracers may hold promise in the future for imaging of NSGCTs. Here, we have reviewed the past efforts and potential future advances in this field. © The Author(s) 2024.
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