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Dermatological Manifestations in Hemodialysis Patients in Iran: A Systematic Review and Meta-Analysis Publisher Pubmed



Asayesh H1 ; Peykari N2 ; Pavareshmasoud M1 ; Esmaeili Abdar M3 ; Tajbakhsh R3 ; Mousavi SM4 ; Djalalinia S5 ; Noroozi M6 ; Qorbani M3, 7 ; Mahdavigorabi A8
Authors
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Authors Affiliations
  1. 1. Department of Medical Emergencies, Qom University of Medical Sciences, Qom, Iran
  2. 2. Iranian Non-communicable Diseases Committee, Ministry of Health and Medical Education, Tehran, Iran
  3. 3. Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
  4. 4. Department of Anesthesiology, Qom University of Medical Sciences, Qom, Iran
  5. 5. Development of Research and Technology Center, Deputy of Research and Technology, Ministry of Health and Medical Education, Tehran, Iran
  6. 6. Social Determinants of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
  7. 7. Chronic Disease Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Department of Basic and Clinical Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Cosmetic Dermatology Published:2019


Abstract

Background: Dermatologic complications are common in patients with end-stage renal disease and also have a high diversity. Objectives: This meta-analysis reviews prevalence of dermatological manifestations among hemodialysis patients in Iran. Materials and Methods: Using PubMed and NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS as the main international electronic data sources, and Iran-Medex, Irandoc, and Scientific Information Database, as the main domestic databases with systematic search capability, we systematically searched surveys, papers, and reports on the prevalence of dermatological manifestations (until February 2016). Heterogeneity of reported prevalence's between studies was assessed using the Q test; overall prevalence of dermatological manifestations was estimated using random-effect meta-analysis model. Results: We found 1229 records; from them, a total of eight studies comprising 917 hemodialysis patients were included. In all of studies, skin discoloration, pruritus and xerosis have the highest prevalence. According to random-effect meta-analysis model, the pooled prevalence of skin discoloration, pruritus, ecchymosis, xerosis, and half-and-half nail in hemodialysis patients were 48.03% (95% CI: 45.09-51.01), 52.85% (95%CI: 49.23-56.47), 19.88 (95% CI: 17.57-22.19), 51.14% (95% CI: 48.25-54.02), and 18.50% (95% CI: 16.0-21.0), respectively. Conclusions: his study shows that the prevalence of dermatological manifestations seems high among the hemodialysis patients in Iran, and skin discoloration, pruritus, and xerosis are more common. © 2018 Wiley Periodicals, Inc.
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