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Systemic Amyloidosis in a Teenage Boy With Inflammatory Bowel Disease Pubmed



Motamed F1 ; Bagherian R1 ; Adalat G1 ; Moradinejad MH1 ; Hajizadeh N1 ; Vasei M2 ; Mehdizadeh M3 ; Rezaei N4, 5, 6
Authors
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Authors Affiliations
  1. 1. Department of Pediatrics, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Pathology, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Radiology, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Acta Medica Iranica Published:2017


Abstract

Systemic amyloidosis is a very rare complication of inflammatory bowel disease (IBD). The reported cases of secondary amyloidosis in children with IBD are much fewer than those reported in adults. Herein, a teenage boy with Crohn’s disease is presented who developed nephrotic syndrome due to renal involvement secondary to amyloidosis, whereas the patient was under treatment with corticosteroid and 6-mercaptopurine. To our best knowledge, this is the first reported case of secondary amyloidosis in a teenage Iranian boy with Crohn’s disease. © 2017, Tehran University of Medical Sciences. All rights reserved.