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Esophageal Perforation in a Patient With Kidney Transplantation Pubmed



Amini M1 ; Abdegah AG2 ; Molavi B2 ; Radmard AR3
Authors
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Authors Affiliations
  1. 1. Department of Nephrology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Surgery, Research Center for Improvement of Surgical Outcomes and Procedures, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Iran

Source: Iranian Journal of Kidney Diseases Published:2016


Abstract

Esophageal perforation is a rupture of the esophageal wall, caused by iatrogenesis in 56% of cases. Perforation of the esophagus remains a challenge, and its incidence has increased as the use of endoscopic procedures has become more frequent. We report a 54-year-old woman with esophageal perforation 8 days after kidney transplantation. She had received a gastrointestinal consultation prior to her transplantation. This report highlights the fact that perforation may occur after any organ transplantation, especially during the initial 2 weeks after transplantation, when mycophenolate mofetil and cyclosporine as well as and high doses of corticosteroid are administered. If there is a delay in passage and a swallowing difficulty, high doses of immunosuppressive drugs are likely to cause ulceration and perforation. Preventive strategies including intravenous steroids for the first 2 to 3 weeks and divided doses of pills should be considered for such patients. © 2016, Iranian Society of Nephrology. All rights reserved.