Evaluation of Respiratory Triggered Diffusion-Weighted Mri With Three B-Values Compared to Adc Map and Fast Spin Echo Heavily T2w in Differential Diagnosis of Hemangioma From Malignant Liver Lesions Publisher Pubmed



Khorram FS^{1, 2} ; Faeghi F² ; Jafarisepehr A³ ; Farshidfar Z⁴
Source: Journal of Medical Imaging and Radiation Sciences Published:2018

Abstract

Purpose: The goal of this study was to evaluate the ability of diffusion-weighted imaging (DWI) with three different b-values compared to apparent diffusion coefficient (ADC) map and fast spin echo heavily T2 weighted (FSE-HT2W) in differential diagnosis of hemangioma from malignant liver lesions. Methods: Fifty-four liver lesions in 20 patients (12 females and eight males: mean age of 52 ± 12.3 years) were examined in this study. FSE-HT2W with breath-hold technique and DWI using respiratory triggered with three different b-values (50,400 and 800 s/mm2) were performed on all patients. Mean ADC values were calculated from each lesion. Agreement levels of each sequence with standard of reference were compared by constructing the receiver operating characteristics (ROC) curve and calculation of the area under the ROC curve. Results: ADC maps had the largest area under the ROC curve and also the most agreement with the standard of reference. DWI obtained with high b-value (b-800 s/mm2) and FSE-HT2W technique were ranked next, respectively. Hemangiomas had significantly higher ADC values than malignant liver lesions (P =.001). No significant differences were seen in gender, age, and lesion size between two lesion groups. Conclusions: ADC maps and DWI in high b-values are more successful than FSE-HT2W technique in differential diagnosis of hemangioma from malignant liver lesions. © 2018