Association Between Atrial Function Assessed by 2D-Speckle Tracking Echocardiography and Albuminuria in Patients With Type 2 Diabetes and Coronary Artery Disease Publisher Pubmed



Moinfar A^{1, 2} ; Hosseinsabet A^{1, 2} ; Sotudehanvary M^{1, 2} Show Affiliations
Source: Journal of clinical ultrasound : JCU Published:2016

Abstract

PURPOSE: We compared left atrial function as assessed by two-dimensional speckle-tracking echocardiography (2DSTE) between patients with type 2 diabetes and coronary artery disease (CAD) with or without albuminuria, nondiabetic patients without CAD, and CAD patients without type 2 diabetes.; METHODS: This cross-sectional study was performed on 112 consecutive patients with CAD (28 nonalbuminuric patients without diabetes, 40 nonalbuminuric patients with type 2 diabetes, and 44 albuminuric patients with type 2 diabetes) and 30 consecutive patients with no CAD, no diabetes, and no albuminuria. Spot urine analysis was performed to measure the urine level of creatinine and albumin. Atrial mechanical variables were measured by 2DSTE.; RESULTS: Although systolic strain and the absolute value of early diastolic strain rate were lower in the CAD groups than in the non-CAD group, there were no significant differences between the CAD groups. Early diastolic strain was lower in the diabetic patients with CAD than in the nondiabetic non-CAD group. There were, however, no significant differences between the CAD groups.; CONCLUSIONS: In our CAD patients, there was no significant association between the presence of type 2 diabetes mellitus and albuminuria and left atrial function, but the reservoir and conduit function of the left atrium were lower in the CAD patients. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 44:561-570, 2016. © 2016 Wiley Periodicals, Inc.