Serostatus of Epstein–Barr Virus in Iranian Ms Patients

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share this content! On (X network) By

Serostatus of Epstein–Barr Virus in Iranian Ms Patients Publisher Pubmed

Karampoor S¹ ; Zahednasab H² ; Pirkouh AA³ ; Monavari SHR³ ; Ramagopalan S⁴ ; Keyvani H³

Show Affiliations

1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Hemmat Highway, Tehran, Iran
2. Institute of Biochemistry and Biophysics, The University of Tehran, Tehran, Iran
3. Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
4. Medical Research Council Functional Genomics Unit and Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, United Kingdom

Source: Acta Neurologica Belgica Published:2016

Abstract

Multiple sclerosis (MS) is a common, complex disorder. Associations of MS with Epstein–Barr virus (EBV) infection in Caucasian populations are well documented. However, in the Iranian population, previous studies have been conflicting. Sixty patients with MS and 50 healthy controls were tested for anti-EBV antibodies using chemiluminescent assays. All MS patients to be seropositive for EBV as compared to 82 % of controls (p = 0.0006). A strong, significant association of MS with EBV infection was documented, similar to studies in first world populations. Future studies should investigate the temporal sequence of infection to try to understand the cause of the recent increase in MS risk in Iran. © 2015, Belgian Neurological Society.

Related Docs

View other Related Docs

1. Smoking and Worsening Disability in Multiple Sclerosis: A Meta-Analysis, Acta Neurologica Scandinavica (2018)

2. The Epidemiologic Trend of Multiple Sclerosis in Razavi Khorasan Province, Iran in Fifteen-Year Period, Multiple Sclerosis and Related Disorders (2025)

3. Differential Serostatus of Epstein-Barr Virus in Iranian Ms Patients With Various Clinical Patterns, Medical Journal of the Islamic Republic of Iran (2018)

4. Increased Serum Brain-Derived Neurotrophic Factor in Multiple Sclerosis Patients on Interferon-B and Its Impact on Functional Abilities, Neurologist (2015)

5. Ebv Infection and Vitamin D in Multiple Sclerosis Patients, Nutrition and Lifestyle in Neurological Autoimmune Diseases: Multiple Sclerosis (2017)

6. Clinical Characteristics and Disability Progression of Early-And Late-Onset Multiple Sclerosis Compared to Adult-Onset Multiple Sclerosis, Journal of Clinical Medicine (2020)

7. Multiple Sclerosis Epidemiology in East Asia, South East Asia and South Asia: A Systematic Review, Neuroepidemiology (2016)

8. Prevalence and Predictors of Dysphagia in Iranian Patients With Multiple Sclerosis, Medical Journal of the Islamic Republic of Iran (2017)

Experts (# of related papers)

View all Related Experts

Mohammad Ali Sahraian (17)

Sharareh Eskandarieh (4)

Other Related Docs

9. Combination Treatment of Docosahexaenoic Acid (Dha) and All-Trans-Retinoic Acid (Atra) Inhibit Il-17 and Rorγt Gene Expression in Pbmcs of Patients With Relapsing-Remitting Multiple Sclerosis, Neurological Research (2018)

10. Molecular Detection of Epstein–Barr Virus, Human Herpes Virus 6, Cytomegalovirus, and Hepatitis B Virus in Patients With Multiple Sclerosis, Middle East Journal of Digestive Diseases (2020)

11. Dysregulation of Micrornas Regulating Survivin in Cd4+ T Cells in Multiple Sclerosis, Multiple Sclerosis and Related Disorders (2020)

12. Consensus Recommendations for the Diagnosis and Treatment of Multiple Sclerosis: 2019 Revisions to the Menactrims Guidelines, Multiple Sclerosis and Related Disorders (2020)

13. Consensus Recommendations for Diagnosis and Treatment of Multiple Sclerosis: 2023 Revision of the Menactrims Guidelines, Multiple Sclerosis and Related Disorders (2024)

14. Quantitative Evaluation of Baff, Hmgb1, Tlr 4 and Tlr 7 Expression in Patients With Relapsing Remitting Multiple Sclerosis, Iranian Journal of Allergy# Asthma and Immunology (2016)

15. Prevalence of Cytomegalovirus in Patients With Multiple Sclerosis: A Case-Control Study in Northern Iran, Jundishapur Journal of Microbiology (2016)

16. Multiple Sclerosis Epidemiology in Middle East and North Africa: A Systematic Review and Meta-Analysis, Neuroepidemiology (2015)

17. Decreased Urinary Level of Melatonin As a Marker of Disease Severity in Patients With Multiple Sclerosis, Iranian Journal of Allergy# Asthma and Immunology (2015)

18. Covid-19 and Its Implications on the Clinico-Radiological Course of Multiple Sclerosis: A Case–Control Study; [Covid-19 Y Sus Implicaciones En El Curso Clinico-Radiologico De La Esclerosis Multiple: Un Estudio De Casos Y Controles], Medicina Clinica (2023)

19. Prevalence and Incidence of Multiple Sclerosis in Tehran, Iran, Iranian Journal of Public Health (2017)

20. Impact of Melatonin on Motor, Cognitive and Neuroimaging Indices in Patients With Multiple Sclerosis, Iranian Journal of Allergy# Asthma and Immunology (2015)

21. Comparison of Cytokine Expression in Multiple Sclerosis Patients and Healthy Volunteers, Acta Medica Iranica (2018)

22. Gray Matter Mri Differentiates Neuromyelitis Optica From Multiple Sclerosis Using Random Forest, Neurology (2016)

23. Infectious Agents and Different Course of Multiple Sclerosis: A Systematic Review, Acta Neurologica Belgica (2018)

24. The Immunomodulatory Effects of All-Trans Retinoic Acid and Docosahexaenoic Acid Combination Treatment on the Expression of Il-2, Il-4, T-Bet, and Gata3 Genes in Pbmcs of Multiple Sclerosis Patients, Neurological Research (2023)

25. Consensus Recommendations for the Diagnosis and Treatment of Multiple Sclerosis: The Middle East North Africa Committee for Treatment and Research in Multiple Sclerosis (Menactrims), Current Medical Research and Opinion (2015)

26. Prevalence and Incidence of Multiple Sclerosis in Ardabil, Northwest of Iran, Multiple Sclerosis and Related Disorders (2021)

27. Increasing Prevalence of Familial Recurrence of Multiple Sclerosis in Iran: A Population Based Study of Tehran Registry 1999-2015, BMC Neurology (2018)

28. The Effect of Traditional Dysphagia Therapy on the Swallowing Function in Patients With Multiple Sclerosis: A Pilot Double-Blinded Randomized Controlled Trial, Journal of Bodywork and Movement Therapies (2019)

29. Genetic Polymorphisms and Epigenetic Regulation of Survivin Encoding Gene, Birc5, in Multiple Sclerosis Patients, BMC Immunology (2019)

31. Design of a Computational Intelligence System for Detection of Multiple Sclerosis With Visual Evoked Potentials, Neuroscience Informatics (2025)

32. Association of Two Polymorphisms in Msh2 and Xrcc1 Genes With Multiple Sclerosis in Iranian Population, Physiology and Pharmacology (2016)

33. Utility of Myelin Basic Protein As an Early Prognostic Biomarker in Multiple Sclerosis, Iranian Red Crescent Medical Journal (2017)

34. An Interleukin 12 B Single Nucleotide Polymorphism Increases Il-12P40 Production and Is Associated With Increased Disease Susceptibility in Patients With Relapsing-Remitting Multiple Sclerosis, Neurological Research (2017)

35. Cost-Effectiveness of Alemtuzumab and Natalizumab for Relapsing-Remitting Multiple Sclerosis Treatment in Iran: Decision Analysis Based on an Indirect Comparison, Journal of Medical Economics (2019)

36. Fluoxetine for Multiple Sclerosis, Cochrane Database of Systematic Reviews (2018)

37. Association Study of Two Functional Single Nucleotide Polymorphisms of Neuropeptide Y Gene With Multiple Sclerosis, Neuropeptides (2016)

38. Increased Expression of Mir-301A in Pbmcs of Patients With Relapsing-Remitting Multiple Sclerosis Is Associated With Reduced Nkrf and Pias3 Expression Levels and Disease Activity, Journal of Neuroimmunology (2018)

Style	Citing Format
MLA	Karampoor S, et al.. "Serostatus of Epstein–Barr Virus in Iranian Ms Patients." Acta Neurologica Belgica, vol. 116, no. 1, 2016, pp. 43-46.
APA	Karampoor S, Zahednasab H, Pirkouh AA, Monavari SHR, Ramagopalan S, Keyvani H (2016). Serostatus of Epstein–Barr Virus in Iranian Ms Patients. Acta Neurologica Belgica, 116(1), 43-46.
Chicago	Karampoor S, Zahednasab H, Pirkouh AA, Monavari SHR, Ramagopalan S, Keyvani H. "Serostatus of Epstein–Barr Virus in Iranian Ms Patients." Acta Neurologica Belgica 116, no. 1 (2016): 43-46.
Harvard	Karampoor S et al. (2016) 'Serostatus of Epstein–Barr Virus in Iranian Ms Patients', Acta Neurologica Belgica, 116(1), pp. 43-46.
Vancouver	Karampoor S, Zahednasab H, Pirkouh AA, Monavari SHR, Ramagopalan S, Keyvani H. Serostatus of Epstein–Barr Virus in Iranian Ms Patients. Acta Neurologica Belgica. 2016;116(1):43-46.
BibTex	@article{ author = {Karampoor S and Zahednasab H and Pirkouh AA and Monavari SHR and Ramagopalan S and Keyvani H}, title = {Serostatus of Epstein–Barr Virus in Iranian Ms Patients}, journal = {Acta Neurologica Belgica}, volume = {116}, number = {1}, pages = {43-46}, year = {2016} }
RIS	TY - JOUR AU - Karampoor S AU - Zahednasab H AU - Pirkouh AA AU - Monavari SHR AU - Ramagopalan S AU - Keyvani H TI - Serostatus of Epstein–Barr Virus in Iranian Ms Patients JO - Acta Neurologica Belgica VL - 116 IS - 1 SP - 43 EP - 46 PY - 2016 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract