Comparison of the Optical Biometry Based on Swept-Source Optical Coherence Tomography and Ultrasound-Based Biometry Device in Patients With Mature Cataract Publisher



M Khorraminejad MASOUD ; M Khodaparast MAHDI ; Gh Ali Ghaith HUSSEIN ; A Majdi ALI ; M Ranjbarpazooki MAHSA ; E Azizi ELHAM
Source: International Journal of Clinical Practice Published:2025

Abstract

Objectives: To compare the agreement and reliability values between an optical biometry based on swept-source optical coherence tomography (OCT) (IOLMaster 700; Carl Zeiss, Germany) and an ocular ultrasound-based biometry device (Nidek; US-4000 Echoscan, Japan) for axial length (AL), anterior chamber depth (ACD), and lens thickness (LT) measurements. Methods: In this cross-sectional study, 101 eyes of 101 consecutive patients with mature cataract underwent routine eye examinations. Then, ocular biometry measurements through optical biometry and contact ultrasound biometry were carried out. The intraclass correlation coefficient (ICC) for reliability and Bland–Altman plots for the agreement between the mean findings of the two devices were analyzed. Results: The mean age of patients was 61.6 ± 13.1 (range, 27–94) years. For AL, the mean differences were small (0.10 mm), but with a very strong correlation and excellent agreement (r = 0.999, ICC = 0.999, p < 0.001) between the two devices. Similarly, for ACD, the correlation was very high with excellent reliability (r = 0.958, ICC = 0.974, p < 0.001), though the ultrasound biometer reported a slightly deeper mean ACD (by 0.13 mm). For LT, the agreement and correlation were lower (r = 0.508, ICC = 0.663, p < 0.001), with the optical biometer reporting a thicker mean LT (0.31 mm) than the ultrasound biometer. Conclusion: AL and ACD measurements from the optical biometry based on swept-source OCT and ultrasound can be used interchangeably in patients with mature cataract. However, LT measurements from the two devices should not be considered interchangeable. © 2025 Elsevier B.V., All rights reserved.