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Chronic Recurrent Multifocal Osteomyelitis: A Case Report Publisher



Farzanefar S1 ; Salehi Y1, 2 ; Abbasi M1 ; Ziaee V3, 4
Authors
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Authors Affiliations
  1. 1. Department of Nuclear Medicine, Vali-asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Children Medical Center, Pediatric Center of Excellence, Tehran, Iran
  3. 3. Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Pediatrics Published:2017


Abstract

Introduction: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare migratory skeletal disorder with non-infectious inflammatory etiology which usually causes bone pain in children and adolescents. Intermittent periods of exacerbation and remission are usually noted during the course of the disease. It is a multifocal bone disease usually involving the metaphyses of long bones. The clinical and Paraclinical findings are non-specific, and indeed CRMO is a diagnosis of exclusion based on multiple criteria. Case Presentation: We present a 6-year-old boy with multiple periods of fever, systemic inflammation and bone pain since he was 2 years old, hospitalized multiple times, received antibiotics and finally diagnosed as a CRMO case. Conclusions: CRMO should be diagnosed according to a variety of clinical and paraclinical findings. In children and adolescents with multiple bone lesions and lytic lesion, one of the differential diagnoses that should be considered is CRMO. © 2017, Iranian Journal of Pediatrics.