The Prevalence of Sexual Dysfunction and Erectile Dysfunction in Men With Multiple Sclerosis: A Systematic Review and Meta-Analysis; [La Prevalencia De La Disfuncion Sexual Y La Disfuncion Erectil En Hombres Con Esclerosis Multiple: Una Revision Sistematica Y Metanalisis] Publisher



Shaygannejad V^{1, 2} ; Mirmosayyeb O^{1, 2, 3} ; Vaheb S² ; Nehzat N² ; Ghajarzadeh M³ Show Affiliations
Source: Neurologia Published:2025

Abstract

Background: The prevalence of sexual dysfunction (SD) in men with multiple sclerosis (MS) is reported variously in different studies. The most common form of SD in these patients is erectile dysfunction (ED). The goal of this systematic review and meta-analysis is to determine the pooled prevalence of SD and ED in men suffering from MS. Methods: We searched PubMed, Scopus, EMBASE, CINAHL, Web of Science, and gray literature (references of references, and congress abstracts) up to 14th November 2020. Results: We found 3163 studies by primary search, 2246 were included after deletion of duplicates. Finally, 29 studies were included for meta-analysis. A total of 3349 patients were evaluated. The pooled prevalence of SD was 66% (95% CI: 64%–69%). The pooled prevalence of erectile dysfunction was 49% (95% CI: 47%–50%). Conclusion: Sexual dysfunction is a prevalent complication of MS in male patients which should be considered by clinicians. © 2022