Hepatitis C in Patients With Multi Blood Transfusion



Kassaian N¹ ; Nokhodian Z¹ ; Babak A² ; Ataei B³ ; Adibi P⁴
Source: Journal of Isfahan Medical School Published:2011

Abstract

Background: Frequent transfusion of blood and blood products to patients with thalassemia major and hemophilia and under hemodialysis patients may cause infections such as hepatitis infection in them.This study aimed to determine the prevalence of hepatitis C and associated risk factors in these patientsin Isfahan, the second big province in Iran.Methods: In a descriptive study, all the patients with hemophilia and thalassemia and under hemodialysisin Isfahan province were enrolled. A questionnaire, including demographic and risk factors ofhepatitis C was completed through a structured interview with closed questions by a trained interviewerfor each patient and HCV-Ab test results were extracted from patient records.Finding: In this study, 60of 570 patients with thalassemia major (10.5%), 232 of 350 patients withhemophilia A and B (66%) and 17 of 800 under hemodialysis patients (2.1%) were positive for hepatitis. Based on Multivariate Logistic Regression model, no independent risk factor was found.Conclusion: Prevalence of hepatitis C in patients with recurrent blood transfusion in Isfahan is high.Since no independent risk factor for hepatitis C disease was found in these three groups, it can be concludedthat multitransfusion is the only predictor for hepatitis C.