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Convalescent Plasma Therapy for Covid-19: Lessons From Sars-Cov, Mers-Cov, and H1n1 Infection Pubmed



Hosseini P1 ; Rahimi H2 ; Najafabadi MM3 ; Ghorbani A4, 10 ; Najafabadi SK5 ; Faridzadeh A6, 11 ; Arabpour J7 ; Khormali E8 ; Deravi N9
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Medical Laboratory Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran
  3. 3. Department of medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Biology, Faculty of Basic Sciences, East Tehran Branch (Ghiamdasht), Islamic Azad University, Tehran, Iran
  5. 5. Department of medicine, Isfahan University of Medical Sciences (IUMS), Isfahan, Iran
  6. 6. Department of Immunology and Allergy, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  7. 7. Student Research Committee, Department of Microbiology, Faculty of New Sciences, Tehran Medical Branch, Islamic Azad University, Tehran, Iran
  8. 8. Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
  9. 9. Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  10. 10. Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  11. 11. Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Acta Medica Indonesiana Published:2021


Abstract

The global widespread mortality after the emergence of SARS-CoV-2 infection in China, has become a critical concern all around the world. Convalescent plasma (CP) therapy is one of the methods elevating the survival rate for COVID-19 infection cases. This technique, as a practicable therapy, was used in previous viral outbreaks including influenza, SARS and MERS. In CP therapy, the blood plasma is collected from persons rehabilitated from that specific infection in order to develop a passive immunity in other patients. Therefore, this review aimed to point out the role of CP therapy in aforementioned viral infections and illustrate different factors influencing the efficacy of CP therapy. © 2021, Indonesian Society of Internal Medicine. All rights reserved.
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