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Reproductive Factors As a Risk Factor for Stemi: A Retrospective Case-Control Study Publisher Pubmed



A Soleimani AZAM ; Fs Khademi Fatemeh SADAT ; Z Soleimani ZAHRA ; Mh Paknahad Mohammad HOSSEIN ; H Roohafza HAMIDREZA ; M Sadeghi MASOUMEH
Authors

Source: Medicine (United States) Published:2025


Abstract

This study explored connections between women's reproductive factors and acute ST-segment elevation myocardial infarction (STEMI). A retrospective case-control study was conducted between 2016 and 2017. The study included 110 women diagnosed with STEMI and 110 control participants. Data on reproductive factors were collected through structured questionnaires and analyzed using statistical methods. Findings showed that increased STEMI risk was associated with longer lactation period, a higher number of parities, gravidity, and abortions. No significant relationships were observed for menopausal status, menopausal age, menarche age, reproductive duration, or oral contraceptive use. This study revealed that higher gravidity, parity, history of abortion, and longer breastfeeding duration were linked to an increased risk of STEMI. However, no significant differences were found between the case and control groups regarding menopausal status, age at menopause, age at menarche, reproductive duration, or oral contraceptive use. © 2025 Elsevier B.V., All rights reserved.
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