Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Pansclerotic Morphea Following Covid-19: A Case Report and Review of Literature on Rheumatologic and Non-Rheumatologic Dermatologic Immune-Mediated Disorders Induced by Sars-Cov-2 Publisher



Lotfi Z1, 2 ; Haghighi A3 ; Akbarzadehpasha A4 ; Mozafarpoor S5 ; Goodarzi A2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Dermatology, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
  2. 2. Department of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Rheumatology, Rasool Akram Medical Complex, Iran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Internal Medicine, Rasool Akram Medical Complex, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Dermatology, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Frontiers in Medicine Published:2021


Abstract

While mucocutaneous manifestations of COVID-19 have been frequently reported and added to our knowledge every day during the pandemic, another issue is the COVID-related diseases that can present as intensified lesions of underlying diseases, a new disease, or changes in the behavior of an old lesion. Given that immune system overreaction and cytokine storm are among the most prominent events in COVID-19, the incidence of autoimmune diseases is expected to increase after COVID-19, as confirmed in several reports. To increase the body of knowledge about short- and long-term outcomes of COVID-19 for specialists, it is essential that similar cases be reported and collected for years to come. The present study investigated a case of pansclerotic morphea that rapidly progressed a few weeks after infection with COVID-19 in a 57-year-old woman with no history of any autoimmune skin or rheumatic diseases. She was prescribed outpatient COVID-19 treatment of azithromycin, vitamins D and C, and then quarantined for 2 weeks. The manifestations of the disease were exacerbated at each follow-up and sampling visit at short intervals. This kind of pansclerotic morphea is reported for the first time. Copyright © 2021 Lotfi, Haghighi, Akbarzadehpasha, Mozafarpoor and Goodarzi.
Related Docs
View other Related Docs
1. A Systematic Review on Mucocutaneous Manifestations of Covid-19 in Children, Iranian Journal of Dermatology (2022)
2. Skin Manifestations As Potential Symptoms of Diffuse Vascular Injury in Critical Covid-19 Patients, Journal of Cutaneous Pathology (2021)
3. A Systematic Review of the Histopathologic Survey on Skin Biopsies in Patients With Corona Virus Disease 2019 (Covid-19) Who Developed Virus or Drug-Related Mucocutaneous Manifestations, Experimental Dermatology (2021)
4. Cutaneous Manifestations and Considerations in Covid-19 Pandemic: A Systematic Review, Dermatologic Therapy (2020)
5. Covid-19 and Exacerbation of Dermatological Diseases: A Review of the Available Literature, Dermatologic Therapy (2021)
6. Covid-19 and Dermatological Manifestations, Atlas of Dermatology, Dermatopathology and Venereology: Cutaneous Infectious and Neoplastic Conditions and Procedural Dermatology (2021)
7. Top 10 Acral Skin Manifestations Associated With Covid-19: A Scoping Review, Dermatologic Therapy (2021)
8. Cutaneous Leukocytoclastic Vasculitis Secondary to Covid-19 Infection: A Case Report, Clinical Case Reports (2021)
Experts (# of related papers)
View all Related Experts
Zahra Pourmoghaddas (4)
Mansour Salesi (3)
Other Related Docs
9. Demographic Characteristics of the Patients With Cutaneous Vasculitis Due to Covid-19 Infection, Indian Journal of Dermatology (2022)
10. A Systematic Review of N-Acetylcysteine for Treatment of Acne Vulgaris and Acne-Related Associations and Consequences: Focus on Clinical Studies, Dermatologic Therapy (2021)
11. Presumed Partial Third Nerve Palsy After Covid-19 Vaccination: A Case Report; [احتمال فلج ناقص عصب سوم پس از واکسیناسیون کووید- :19گزارش یک مورد], Journal of Isfahan Medical School (2024)
12. Clinical, Laboratory and Imaging Characteristics, and Outcomes of Hospitalized Children With Suspected Covid-19 Infection: A Report From Isfahan-Iran, Journal of Research in Medical Sciences (2022)
13. Autoimmune Encephalitis Due to Covid-19 in a Young Patient, Iranian Journal of Child Neurology (2023)
14. A Narrative Review of Covid-19: The New Pandemic Disease, Iranian Journal of Medical Sciences (2020)
15. Erythema Multiform-Like Lesions in a Patient Infected With Sars-Cov-2: A Case Report, Future Virology (2021)
16. Risk Factors of Covid-19 Associated Mucormycosis in Iranian Patients: A Multicenter Study, BMC Infectious Diseases (2024)
17. Blood Cell Morphology and Covid-19 Clinical Course, Severity, and Outcome, Journal of Hematopathology (2021)
18. Newly Diagnosed Glomerulonephritis During Covid-19 Infection Undergoing Immunosuppression Therapy, a Case Report, Iranian Journal of Kidney Diseases (2020)
19. Neuropsychiatric Manifestations of Covid-19 in Hospitalized Pediatrics: A Multicenter Cross-Sectional Study, Archives of Pediatric Infectious Diseases (2023)
20. Risk Factors, Clinical, and Laboratory Characteristics of Patients With a Diagnosis of Covid-19, Journal of Emergency Practice and Trauma (2022)
21. Age-Dependent Clinical Features and Prognosis of Covid-19 Patients, Tanaffos (2021)
22. The Covid-19 Pandemic: A Systematic Review of the Current Evidence; [Пандемия Covid-19: Систематический Обзор Современных Данных], Russian Journal of Infection and Immunity (2020)
23. Sars-Cov-2 (Covid-19): New Discoveries and Current Challenges, Applied Sciences (Switzerland) (2020)
24. The Severity of Symptoms and Outcomes of Patients Admitted With Rheumatic Diseases and Covid-19; a Prospective Cohort Study in Iran, Immunopathologia Persa (2021)
25. Covid-19 Management in the Emergency Ward, Journal of Research in Medical Sciences (2021)
26. A Comprehensive Review of Therapeutic Options for Covid-19, Ethiopian Journal of Health Development (2022)
27. Aspects of Epidemiology, Pathology, Virology, Immunology, Transmission, Prevention, Prognosis, Diagnosis, and Treatment of Covid.19 Pandemic: A Narrative Review, International Journal of Preventive Medicine (2021)
28. Unexpected Positive Effects of Rituximab and Corticosteroids on Covid-19 in a Patient Suffering From Granulomatosis With Polyangiitis, Advanced Biomedical Research (2021)
29. Clinical Display, Diagnostics and Genetic Implication of Novel Coronavirus (Covid-19) Epidemic, European Review for Medical and Pharmacological Sciences (2020)
30. Movement Disorders Associated With Covid-19, Parkinson's Disease (2021)
31. The Seroprevalence and Seropositivity of Sars-Cov-2 Among Healthcare Workers During the Third Pandemic Wave, Antibodies (2023)
32. Autoimmune Versus Non-Autoimmune Cutaneous Features in Monogenic Patients With Inborn Errors of Immunity, Biology (2023)
33. Laboratory Findings of Covid-19 Infection Are Conflicting in Different Age Groups and Pregnant Women: A Literature Review, Archives of Medical Research (2020)
34. Successful Recovery of a Child With Covid-19-Induced Secondary Hemophagocytic Lymphohistiocytosis, Archives of Pediatric Infectious Diseases (2022)
35. Effectiveness of Corticosteroid Therapy in Patients With Moderate to Severe Coronavirus Disease 2019: A Retrospective Study, Journal of Nephropharmacology (2023)
36. Investigating Methods for Coronavirus Disease 2019 Control: A Systematic Review, Polish Annals of Medicine (2021)
37. Clinical Symptoms of Covid-19 and Their Association With Disease Outcome, Advanced Biomedical Research (2022)
38. Characteristics of Children With Kawasaki Disease-Like Signs in Covid-19 Pandemic: A Systematic Review, Frontiers in Pediatrics (2021)
39. Clinical Signs, Symptoms, and Severity of Covid-19 in Patients With Rheumatic Diseases During the Covid-19 Epidemic, Immunopathologia Persa (2024)
40. Abdominal Signs and Symptoms of Covid-19 in Children, Archives of Pediatric Infectious Diseases (2021)
41. Guillain-Barre Syndrome (Gbs) After Severe/Critical Covid-19 or Covid-19 Vaccination, European journal of medical research (2025)
42. Covid-19 and Acute Pancreatitis: A Case Report, Acta Medica Iranica (2021)
43. Abrupt Bilateral Blindness As a Rare Post-Acute Demyelinating Consequence of Covid-19, eNeurologicalSci (2022)
44. Health Psychology and Coronavirus Pandemic Crisis (Covid-19): A Review Study, Journal of Isfahan Medical School (2020)
45. Adrenal Insufficiency in Coronavirus Disease 2019 (Covid-19)-Infected Patients Without Preexisting Adrenal Diseases: A Systematic Literature Review, International Journal of Endocrinology (2021)
46. Epidemiological Status and Health System Screening of Covid 19 Hospitalized Patients in Isfahan, Iran, Medical Journal of the Islamic Republic of Iran (2022)