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Evaluation of the Mean Percentages of the Peripheral Blood Gamma Delta T Lymphocytes in the Healthy Subjects and Celiac Patients in Isfahan



Abtahi A1 ; Emami MH2 ; Alsahebfosoul F1 ; Masjedi M1 ; Saffaei A3
Authors
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Authors Affiliations
  1. 1. Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Gastroenterology and Hepatology, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Pharmacy Stu.' Research Committee, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Govaresh Published:2015

Abstract

Background: An elevation in the mean percentages of the gamma delta T lymphocytes per total T cells in the epithelium of the small intestine has a diagnostic value for celiac disease. This study aimed to measure the percentages of the peripheral blood gamma delta T lymphocytes in the adults' celiac disease and healthy controls. Materials and Methods: In this case-control study the absolute numbers of the peripheral blood lymphocytes obtained from the controls (n = 21) and celiac patients (n=15) were studied, Using a cell counter. The proportions of the gamma-delta T lymphocytes were evaluated by the flow cytometer method. Results: The results showed that there was not significant I difference in the percentages of the gamma-delta T lymphocytes between celiac patients and healthy individuals. (p value= 0.84) Conclusion: Collectively, the data show that the percentages of the peripheral blood gamma delta T lymphocytes could not be helpful for celiac disease diagnosis.