Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Prevalence and Risk Factors for Urinary Tract Infection in Kidney Transplant Recipients in the First Year After Transplantation Publisher



Hosseini VS1 ; Vahdat S2 ; Shahidi S2 ; Atapour A2 ; Mohsen S1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Isfahan Kidney Disease Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Isfahan Kidney Disease Research Center, Khorshid Hospital, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Nephro-Urology Monthly Published:2022


Abstract

Background: End-stage renal disease (ESRD) needs replacement therapy and most often, kidney transplantation is the best therapeutic option. Urinary tract infection (UTI) is one of the most important complications after renal transplantation that affects transplantation outcomes. Objectives: This study aimed to define the incidence rate, UTI risk factors among kidney transplant recipients, and causative organism of UTI and their antibiotic susceptibility. Methods: In this cross-sectional study, we collected clinical, demographic, and laboratory data from 268 transplant recipients in Ali-Asghar Hospital from 2011-2018. Data collected from patients were analyzed with SPSS software version 25. Results: According to the results, 50 (18.7%) had UTI in the first year after renal transplantation. Female gender and underlying cause of renal failure were predisposing factors for UTI. The most common causative organism was Escherichia coli (58.4%). The antibiotic susceptibility results showed nitrofurantoin and meropenem as the most effective antibiotics for Escherichia coli. Conclusions: The UTI was more common in women and patients with analgesic nephropathy and lupus nephritis. The most common causative organism was E. coli and meropenem and nitrofurantoin were the most effective drug choices. © 2022, Author(s).
Related Docs
View other Related Docs
1. Molecular Assessment of Microbial Etiology in Urinary Tract Infection in Renal Transplant Patients With Fever, Journal of Isfahan Medical School (2018)
2. Characterization of Extended-Spectrum Β-Lactamase-Producing Uropathogenic Escherichia Coli Among Iranian Kidney Transplant Patients, Infection and Drug Resistance (2020)
3. Susceptibility Pattern of E. Coli-Associated Urinary Tract Infection (Uti): A Comparison of Spinal Cord Injury-Related and Nosocomial Uti, Medical Science Monitor (2009)
4. High Frequency of Integrons and Efflux Pump in Uropathogenic Escherichia Coli Isolated From Iranian Kidney and Non-Kidney Transplant Patients, Gene Reports (2020)
5. Investigation of Nosocomial Urinary Tract Infections Post Transplantation, Main Pathogens, and Sensitivity Tests, Current Drug Therapy (2024)
6. Antimicrobial Resistance in Hospitalized Patients With Community Acquired Urinary Tract Infection in Isfahan, Iran, Archives of Iranian Medicine (2021)
7. The Causative Agents and Antibiotic Susceptibility Patterns of Healthcare-Associated Urinary Tract Infections (Hautis) in Isfahan, Iran: The Impact on Empiric Therapy, Nephro-Urology Monthly (2023)
8. Pathogenic Features of Urinary Escherichia Coli Strains Causing Asymptomatic Bacteriuria During Pregnancy, Gene Reports (2022)
Experts (# of related papers)
View all Related Experts
Behrooz Ataei (5)
Seyed Asghar Havaei (5)
Other Related Docs
9. Characterization of Plasmid-Mediated Quinolone Resistance and Serogroup Distributions of Uropathogenic Escherichia Coli Among Iranian Kidney Transplant Patients, BioMed Research International (2020)
10. Antibiotic Susceptibility Patterns of Isolates From Children With Urinary Tract Infection in Isfahan, Iran: Impact on Empirical Treatment, Journal of Global Antimicrobial Resistance (2017)
11. High Prevalence of Multidrug-Resistance Uropathogenic Escherichia Coli Strains, Isfahan, Iran, Journal of Natural Science, Biology and Medicine (2016)
12. Nosocomial Urinary Tract Infections in a Tertiary Hospital; Preliminary Study of Antibiotics Susceptibility Testing and Pathogen Types, Anti-Infective Agents (2024)
13. Antibiotic Resistant Pattern in Escherichia Coli Derived From Outpatients and Inpatients With Urinary Tract Infections in Alzahra Hospital, Isfahan, Iran, Journal of Isfahan Medical School (2017)
14. Intestinal Parasitic Infections in Renal Transplant Recipients, Brazilian Journal of Infectious Diseases (2010)
15. Phylogenetic Group Distribution of Uropathogenic Escherichia Coli and Related Antimicrobial Resistance Pattern: A Meta-Analysis and Systematic Review, Frontiers in Cellular and Infection Microbiology (2022)
16. High Frequency of Integron-Associated Cassette Arrays Containing Dfra and Aad Genes in Urinary Isolates of Escherichia Coli in the Southwest of Iran, Molecular Genetics, Microbiology and Virology (2021)
17. Molecular Epidemiology of Bla Ctx-M Gene-Producing Uropathogenic Escherichia Coli Among Iranian Kidney Transplant Patients: Clonal Dissemination of Cc131 and Cc10, Annals of Clinical Microbiology and Antimicrobials (2021)
18. Covid-19 Impact on Lower Urinary Tract Symptoms of Kidney Transplantation Recipients, Translational Research in Urology (2022)
19. A Comparison of Antibiotic Susceptibility Patterns of Klebsiella Associated Urinary Tract Infection in Spinal Cord Injured Patients With Nosocomial Infection, Acta Medica Iranica (2009)
20. Intestinal Parasitic Infections in Renal Transplant Recipients, Annals of Tropical Medicine and Public Health (2011)
21. Intestinal Fungal and Parasitic Infections in Kidney Transplant Recipients: A Multi-Center Study., Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (2012)
22. Characterization of Clonal Groups of Antibiotic-Resistant Biofilm-Forming Staphylococcus Aureus Strains Isolated From Patients With Urinary Tract Infections in Isfahan, Iran, Archives of Clinical Infectious Diseases (2024)
23. Prevalence of Ctx-M Genes in Escherichia Coli Strains in Outpatient and Inpatient Cases With Urinary Tract Infections in Isfahan, Iran, Journal of Isfahan Medical School (2016)
24. Frequency and Antibiotic Resistance of Hybrid Entroaggregative/Uropathogenic Escherichia Coli Isolated From Patients Hospitalized in Isfahan, Iran, Infection, Epidemiology and Microbiology (2021)
25. Prevalence of Esbls and Biofilm Formation in Escherichia Coli Isolated From Urinary Tract Infection in Isfahan, Iran, Infection, Epidemiology and Microbiology (2022)
26. Frequency Assessment of Β-Lactamase Enzymes in Escherichia Coli and Klebsiella Isolates in Patients With Urinary Tract Infection, Journal of Research in Medical Sciences (2014)
27. Prevalence of Nosocomial Infections and the Pattern of Microbial Resistance in a Tertiary Care Referral Hospital (Alzahra), Isfahan, Iran, New Emirates Medical Journal (2024)
28. The Global Prevalence of Class 1 Integron and Associated Antibiotic Resistance in Escherichia Coli From Patients With Urinary Tract Infections, a Systematic Review and Meta-Analysis, Microbial Drug Resistance (2020)
29. Prevalence and Antibiotic Susceptibility Patterns of Extended-Spectrum ß-Lactamase and Metallo-ß-Lactamase-Producing Uropathogenic Escherichia Coli Isolates, Laboratory Medicine (2014)
30. Characterization of Hypervirulent Extended-Spectrum Β-Lactamase-Producing Klebsiella Pneumoniae Among Urinary Tract Infections: The First Report From Iran, Infection and Drug Resistance (2020)
31. The Antibiotic Resistance Profiles of Bacterial Strains Isolated From Patients With Hospital-Acquired Bloodstream and Urinary Tract Infections, Critical Care Research and Practice (2012)
32. Evaluation of the Incidence and Risk Factors of Urine Leakage Following Kidney Transplantation, Journal of Isfahan Medical School (2007)
33. Preliminary Study of Antibiotics Susceptibility Testing and Pathogens Associated With Nosocomial Infections in a Tertiary Hospital, Anti-Infective Agents (2024)
34. Antimicrobial Efficacy and Prevalence of Microcins: Low Molecular Mass Bacteriocins Produced by Escherichia Coli, International Journal of Peptide Research and Therapeutics (2023)
35. Common Microbial Causes of Significant Bacteriuria and Their Antibiotic Resistance Pattern in the Isfahan Province of Iran, Journal of Chemotherapy (2018)
36. Candida Urinary Tract Infection Among Icu Patients in Isfahan, Iran, Archives of Clinical Infectious Diseases (2019)
37. Virulence Genes and Phylogenetic Groups of Uropathogenic Escherichia Coli Isolates From Patients With Urinary Tract Infection and Uninfected Control Subjects: A Case-Control Study, BMC Infectious Diseases (2021)