Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Causative Agents of Onychomycosis: A 7-Year Study Publisher Pubmed



Chadeganipour M1 ; Mohammadi R1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Clinical Laboratory Analysis Published:2016


Abstract

Background: Onychomycosis is principally caused by dermatophyte species, but nondermatophyte molds and yeasts have also been involved, causing different clinical manifestations. The aim of this investigation is to determine the clinicomycological and epidemiological profile of the etiologic agents of onychomycosis. Methods: The study population included 9,785 suspected cases of onychomycosis referred to the Medical Mycology Reference Laboratory in Isfahan, Iran, during 2007–2014. Nail clipping was collected in sterile Petri dishes for direct microscopic examination and culture. Clinical isolates were identified by using phenotypic tests and molecular techniques. Results: Of total 9,785 cases with clinical suspicion of onychomycosis comprised in the present study, 1,284 patients (13.1%) were positive by direct microscopy. Age range of patients was between 1 and 82 years. Housewives were the commonest infected population. Candida albicans was the most prevalent species isolated from patients in this study (34.9%) followed by Trichophyton interdigitale (11.7%) and Aspergillus flavus (9.1%). Conclusion: The pattern of causative agents and clinical signs of onychomycosis is altering region to region, so repeated epidemiological surveys of onychomycosis seems to be fundamental. The present study provides novel and appropriate epidemiologic data of onychomycosis for the better prevention and treatment of this fungal infection. © 2016 Wiley Periodicals, Inc.
Related Docs
View other Related Docs
1. Growing Incidence of Non-Dermatophyte Onychomycosis in Tehran, Iran, Jundishapur Journal of Microbiology (2016)
2. Study of Onychomycosis in Isfahan, Iran, Mycoses (2010)
3. The First Case of Fingernail Onychomycosis Due to Neoscytalidium Novaehollandiae, Molecular Identification and Antifungal Susceptibility, Journal de Mycologie Medicale (2020)
4. An Alarming Rise of Non-Albicans Candida Species and Uncommon Yeasts in the Clinical Samples; a Combination of Various Molecular Techniques for Identification of Etiologic Agents, BMC Research Notes (2019)
5. Translation Elongation Factor 1-Alpha Gene As a Marker for Diagnosing of Candidal Onychomycosis, Current Medical Mycology (2020)
6. Candida Infections Among Neutropenic Patients, Caspian Journal of Internal Medicine (2016)
7. Otomycosis Due to the Rare Fungi Talaromyces Purpurogenus, Naganishia Albida and Filobasidium Magnum, Mycopathologia (2020)
8. Caspofungin-Non-Susceptible Candida Orthopsilosis Isolated From Onychomycosis in Iran, Iranian Journal of Public Health (2017)
Experts (# of related papers)
View all Related Experts
Rasoul Mohammadi (36)
Seyed Hossein Mirhendi Esfahani (27)
Other Related Docs
9. Identification of Dermatophyte and Nondermatophyte Molds Isolated From Animal Lesions Suspected to Dermatomycoses, Advanced Biomedical Research (2020)
10. Evaluation of Prevalence of New Candida Species (C. Orthopsilosis and C. Metapsilosis) Among C. Parapsilosis Group Isolated From Patients by Pcr-Rflp of Sadh Gene in Iran, Journal of Isfahan Medical School (2011)
11. Molecular Identification of Candida Species Isolated From Gastrooesophageal Candidiasis in Tehran, Iran, Gastroenterology and Hepatology from Bed to Bench (2015)
12. Use of Restriction Fragment Length Polymorphism to Rapidly Identify Dermatophyte Species Related to Dermatophytosis, Jundishapur Journal of Microbiology (2015)
13. Species Identification and in Vitro Antifungal Susceptibility Testing of Aspergillus Section Nigri Strains Isolated From Otomycosis Patients, Journal de Mycologie Medicale (2018)
14. Comparison of in Vitro Activities of Newer Triazoles and Classic Antifungal Agents Against Dermatophyte Species Isolated From Iranian University Hospitals: A Multi-Central Study, Annals of Clinical Microbiology and Antimicrobials (2023)
15. A Molecular Epidemiological Survey of Clinically Important Dermatophytes in Iran Based on Specific Rflp Profiles of Beta-Tubulin Gene, Iranian Journal of Public Health (2013)
16. Otomycosis in Western Iran: Clinical and Mycological Aspects, Archives of Clinical Infectious Diseases (2017)
17. Otomycosis in Central Iran: A Clinical and Mycological Study, Iranian Red Crescent Medical Journal (2011)
18. Identification and Frequency of Candida Species in Patients With Different Forms of Candidiasis in Isfahan, Using Pcr-Rflp Method, Journal of Isfahan Medical School (2011)
19. Differentiation of Candida Albicans Complex Species Isolated From Invasive and Non-Invasive Infections Using Hwp1 Gene Size Polymorphism, Current Medical Mycology (2021)
20. Species Distribution and Susceptibility Profiles of Oral Candidiasis in Hematological Malignancy and Solid Tumor Patients, Brazilian Journal of Microbiology (2023)
21. In Vitro Susceptibility Patterns of Clinically Important Trichophyton and Epidermophyton Species Against Nine Antifungal Drugs, Mycoses (2015)
22. Antifungal Activity of Anethum Graveolens Extract and Atrovastatin Against Candida Species Compared to Fluconazole, Journal of Isfahan Medical School (2015)
23. Candidemia in Children Caused by Uncommon Species of Candida, Archives of Pediatric Infectious Diseases (2018)
24. Antifungal Effect of Atorvastatin Against Candida Species in Comparison to Fluconazole and Nystatin, Medicine and Pharmacy Reports (2019)
25. Detection of Dermatophytes From Dermatophytosis-Suspected Cases in Iran, Evaluation of Polymerase Chain Reaction-Sequencing Method, Advanced Biomedical Research (2020)
26. A 10-Year Study of Dermatophytoses in Isfahan, Iran, Journal of Clinical Laboratory Analysis (2016)
27. Molecular Identification of Causative Agents in 25 Cases With Mucormycosis in Iran, Archives of Clinical Infectious Diseases (2019)
28. Low Level of Antifungal Resistance in Iranian Isolates of Candida Glabrata Recovered From Blood Samples in a Multicenter Study From 2015 to 2018 and Potential Prognostic Values of Genotyping and Sequencing of Pdr1, Antimicrobial Agents and Chemotherapy (2019)
29. The Frequency of Oral Candidiasis in Children and Adolescents With Leukemia in Isfahan Province, Iran, Journal of Isfahan Medical School (2017)
30. Fusarium Proliferatum-Induced Chronic Lip Ulcer: Successful Treatment With Itraconazole: A Case Report, Journal of Medical Case Reports (2022)
31. Identification of Candida Species Isolated From Candiduria Patients Using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism in Isfahan, Iran, Journal of Isfahan Medical School (2016)
32. Epidemiology and Antifungal Susceptibility of Candida Species Isolated From 10 Tertiary Care Hospitals in Iran, Microbiology Spectrum (2022)
33. Development a Diagnostic Pan-Dermatophyte Taqman Probe Real-Time Pcr Assay Based on Beta Tubulin Gene, Mycoses (2016)
34. Fungal Sinusitis and Treatment, Journal of Isfahan Medical School (2010)
35. The Epidemiology of Dermatophytosis Among Elementary School Children in Koohrang City, Iran, in 2014 and 2015, Journal of Isfahan Medical School (2015)
36. Epidemiologic and Antifungal Susceptibility Profile of Candiduria Among Patients Hospitalized in the Nephrology and Intensive Care Unit Wards, Tehran, Iran, Jundishapur Journal of Microbiology (2022)
37. Utilization of Size Polymorphism in Its1 and Its2 Regions for Identification of Pathogenic Yeast Species, Journal of Medical Microbiology (2017)
38. A Simple Multiplex Polymerase Chain Reaction Assay for Rapid Identification of the Common Pathogenic Dermatophytes: Trichophyton Interdigitale, Trichophyton Rubrum, and Epidermophyton Floccosum, Current Medical Mycology (2021)
39. Frequency of Uncommon Clinical Yeast Species Confirmed by Its-Sequencing, Archives of Clinical Infectious Diseases (2019)
40. Candida Africana Vulvovaginitis: Prevalence and Geographical Distribution, Journal de Mycologie Medicale (2020)
41. Rapid Detection of Candida Species in Bronchoalveolar Lavage Fluid From Patients With Pulmonary Symptoms, Brazilian Journal of Microbiology (2016)
42. Molecular Characterization of Candida Dubliniensis and Candida Albicans in the Oral Cavity of Drug Abusers Using Duplex Polymerase Chain Reaction, Current Medical Mycology (2018)
43. Microbial Epidemiology of Candidaemia in Neonatal and Paediatric Intensive Care Units at the Children's Medical Center, Tehran, Mycoses (2018)
44. Candida Palmioleophila Candidemia and Bacterial Co-Infection in a 3-Month-Old Infant With Biliary Atresia, Frontiers in Cellular and Infection Microbiology (2023)
45. Multicenter Identification and Antifungal Susceptibility Patterns of Candida Species Isolated From Clinical Samples, Jundishapur Journal of Microbiology (2017)
46. The Frequency of Candiduria in Hospitalized Patients at Nephrology Department, Labbafinejad Hospital, Tehran, Iran, Journal of Isfahan Medical School (2017)
47. Identification of Candida Species and Antifungal Susceptibility in Cancer Patients With Oral Lesions in Ahvaz, Southern West of Iran, Advanced Biomedical Research (2020)
48. Molecular Epidemiology of Otomycosis in Isfahan Revealed a Large Diversity in Causative Agents, Journal of Medical Microbiology (2019)
49. Frequency Distribution of Keratinophilic Dermatophyte Fungi From the Soil of Different Zones in Isfahan Using Morphological and Molecular Methods, Advanced Biomedical Research (2019)
50. Artifacts Similar to Fungal Elements in Medical Mycology Laboratories, Journal of Isfahan Medical School (2014)