Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Risk Factors for In-Hospital Mortality Among Patients With Coronavirus-19 in Isfahan City, Iran Publisher

Summary: Study identifies older age, COPD, high WBC, low Hb, ARDS, and ICU admission as mortality risk factors in COVID-19 patients. #COVID19 #MortalityRisk

Riahi R1 ; Ghasemi M2 ; Shatouri ZM3 ; Gharipour M4 ; Maghami M1 ; Melali H5 ; Sami R6 ; Tabatabaei A7 ; Hosseini SM1
Authors

Source: Advanced Biomedical Research Published:2022


Abstract

Background: The aim of the study is to explore the risk factors of mortality for hospitalized patients in three designated hospitals in Isfahan province. Materials and Methods: This retrospective cohort study was conducted on all positive coronavirus disease (COVID)-19 patients admitted to Khorshid, Isabn Maryam, and Amin hospitals in Isfahan province. The demographic, clinical, laboratory, and outcome data of patients who were died or discharged from February 24, 2020, to April 18, 2020, were extracted from patient’s medical records. Results: Overall 1044 COVID-19 patients were included in this analysis. Based on the findings of this study, older age (≥65 years) (adjusted hazard ratio [aHR]: 2.06; 95% confidence interval [CI]: 1.13–3.76), chronic obstructive pulmonary disease (COPD) history (aHR: 2.52; 95% CI: 1.09–5.83), white blood cell (WBC) counts more than 10 × 10^3/L (aHR: 3.05; 95% CI: 1.42–6.55), Hb level <13 gr/L (aHR: 2.82; 95% CI: 1.34–5.93), bilateral pulmonary infiltrates (aHR: 2.02; 95% CI: 1.12–3.64) at admission, development of acute respiratory distress syndrome (ARDS) (aHR: 1.87; 95% CI: 1.01–3.47), and intensive care unit (ICU) admission (aHR: 2.09; 95% CI: 1.04–4.18) during hospitalization were risk factors for in-hospital mortality in patients with COVID-19. Conclusions: Multiple factors were found related to the severity and death among COVID-19 patients. We were found that older age (≥65 years) with COPD history, high level of WBC, low level of Hb (<13 g/L), bilateral pulmonary infiltrates at admission, development of ARDS, and ICU admission during hospitalization were identified as risk factors of death among COVID-19 patients. More related studies are needed in the future. © 2022 Advanced Biomedical Research.
Related Docs
View other Related Docs
1. Age-Dependent Clinical Features and Prognosis of Covid-19 Patients, Tanaffos (2021)
2. Multivariable Analysis of Clinical and Laboratory Data Manifestations Predicting Severity and Mortality Risk in Patients With Coronavirus Disease 2019 in the Mountainous West of Iran: A Retrospective Single-Center Study, Asian Biomedicine (2022)
3. Severity of Disease and Covid-19 Complications During Hospital Stay: A Prospective Cohort Study, Archives of Iranian Medicine (2022)
Experts (# of related papers)
View all Related Experts
Ramin Sami (6)
Marjan Mansourian (6)
Risk Factors for In-Hospital Mortality Among Patients With Coronavirus-19 in Isfahan City, Iran
Other Related Docs
4. Risk Factors Associated With Severity and Death From Covid-19 in Iran: A Systematic Review and Meta-Analysis Study, Journal of Intensive Care Medicine (2023)
5. Risk Factors, Clinical, and Laboratory Characteristics of Patients With a Diagnosis of Covid-19, Journal of Emergency Practice and Trauma (2022)
6. Rehabilitation, a Necessity in Hospitalized and Discharged People Infected With Covid-19: A Narrative Review, Physical Therapy Reviews (2021)
7. Association of the Medication Protocols and Longitudinal Change of Covid-19 Symptoms: A Hospital-Based Mixed-Statistical Methods Study, Journal of Biopharmaceutical Statistics (2024)
8. The Negative Impact of Obesity on the Occurrence and Prognosis of the 2019 Novel Coronavirus (Covid-19) Disease: A Systematic Review and Meta-Analysis, Eating and Weight Disorders (2022)
9. Cancer Care Management During the Covid-19 Pandemic, Risk Management and Healthcare Policy (2020)
10. Predicting Covid-19 Hospital Stays With Kolmogorov–Gabor Polynomials: Charting the Future of Care, Information (Switzerland) (2023)
11. The Lived Experience of Nurses Caring for Patients With Covid-19 in Iran: A Phenomenological Study, Risk Management and Healthcare Policy (2020)
12. The Clinical Manifestation and Outcome of Covid-19 in Patients With a History of Ischemic Heart Disease; a Retrospective Case-Control Study, BMC Cardiovascular Disorders (2023)
13. Differential Diagnostic Utility of Clinical Laboratory Data in Patients With Severe and Non-Severe Covid-19, Shiraz E Medical Journal (2022)
14. Corona Virus Disease 2019 (Covid-19) and Its Effect on Renal System, a Systematic Review and Meta-Analysis, Iranian Journal of Kidney Diseases (2020)
15. Cardiovascular Risk Factors and Clinical Outcomes Among Patients Hospitalized With Covid-19: Findings From the World Heart Federation Covid-19 Study, Global Heart (2022)
16. Is Non-Invasive Ventilation a Good Choice in All Patients With Severe Covid-19? a Cohort Retrospective Study, Tanaffos (2024)
17. Comparison of Clinical Outcomes, Demographic, and Laboratory Characteristics of Hospitalized Covid-19 Patients During Major Three Waves Driven by Alpha, Delta, and Omicron Variants in Tehran, Iran, Influenza and other Respiratory Viruses (2023)
18. Epidemiological Status and Health System Screening of Covid 19 Hospitalized Patients in Isfahan, Iran, Medical Journal of the Islamic Republic of Iran (2022)
19. Bacterial Infections and Outcomes of Inpatients With Covid-19 in the Intensive Care Unit During the Delta-Dominant Phase: The Worst Wave of Pandemic in Iran, Frontiers in Public Health (2024)
20. Evaluation of Epidemiologic, Clinical and Laboratory Findings of Covid-19 Patients in Intensive Care Units, Alzahra Hospital; [بررسی یافته‌های اپیدمیولوژیک، بالینی و آزمایشگاهی بیماران مبتلا به کووید-19 بستری در بخش‌های مراقبت ویژه بیمارستان الزهرا (س)], Journal of Isfahan Medical School (2024)