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Skin Melanoma Detection in Microscopic Images Using Hmm-Based Asymmetric Analysis and Expectation Maximization Publisher Pubmed



Rastghalam R1 ; Danyali H1 ; Helfroush MS1 ; Celebi ME2 ; Mokhtari M3
Authors
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Authors Affiliations
  1. 1. Elcetrical Engineering, Shiraz University of Technology, Fars, Shiraz, Iran
  2. 2. Department of Computer Science, University of Central Arkansas, Conway, AR, United States
  3. 3. Isfahan University of Medical Sciences, Isfahan, Iran

Source: IEEE Journal of Biomedical and Health Informatics Published:2021


Abstract

Melanoma is one of the deadliest types of skin cancer with increasing incidence. The most definitive diagnosis method is the histopathological examination of the tissue sample. In this paper, a melanoma detection algorithm is proposed based on decision-level fusion and a Hidden Markov Model (HMM), whose parameters are optimized using Expectation Maximization (EM) and asymmetric analysis. The texture heterogeneity of the samples is determined using asymmetric analysis. A fusion-based HMM classifier trained using EM is introduced. For this purpose, a novel texture feature is extracted based on two local binary patterns, namely local difference pattern (LDP) and statistical histogram features of the microscopic image. Extensive experiments demonstrate that the proposed melanoma detection algorithm yields a total error of less than 0.04%. © 2013 IEEE.