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An International Perspective on Hospitalized Patients With Viral Community-Acquired Pneumonia Publisher Pubmed



Radovanovic D1 ; Sotgiu G2 ; Jankovic M3 ; Mahesh PA4 ; Marcos PJ5 ; Abdalla MI6 ; Di Pasquale MF7 ; Gramegna A7 ; Terraneo S8, 10 ; Blasi F7 ; Santus P1 ; Aliberti S7 ; Reyes LF9 ; Restrepo MI6 Show All Authors
Authors
  1. Radovanovic D1
  2. Sotgiu G2
  3. Jankovic M3
  4. Mahesh PA4
  5. Marcos PJ5
  6. Abdalla MI6
  7. Di Pasquale MF7
  8. Gramegna A7
  9. Terraneo S8, 10
  10. Blasi F7
  11. Santus P1
  12. Aliberti S7
  13. Reyes LF9
  14. Restrepo MI6
  15. Aruj PK11
  16. Attorri S12
  17. Barimboim E13
  18. Caeiro JP14
  19. Garzon MI14
  20. Cambursano VH15
  21. Ceccato A16
  22. Chertcoff J17
  23. Cordon Diaz A18
  24. De Vedia L19
  25. Ganaha MC20
  26. Lambert S21
  27. Lopardo G22
  28. Luna CM23
  29. Malberti AG24
  30. Morcillo N25
  31. Tartara S25
  32. Pensotti C26
  33. Pereyra B27
  34. Scapellato PG28
  35. Stagnaro JP29
  36. Shah S30
  37. Lotsch F31
  38. Thalhammer F31
  39. Anseeuw K32
  40. Francois CA33
  41. Van Braeckel E34
  42. Vincent JL35
  43. Djimon MZ36
  44. Aranha Nouer S37
  45. Chipev P38
  46. Encheva M38
  47. Miteva D39
  48. Petkova D40
  49. Balkissou AD41
  50. Pefura Yone EW42
  51. Mbatchou Ngahane BH43
  52. Shen N44
  53. Xu JF45
  54. Bustamante Rico CA46
  55. Buitrago R46
  56. Pereira Paternina FJ47
  57. Kayembe Ntumba JM48
  58. Vladiccarevic V49
  59. Jakopovic M50
  60. Matkovic Z51
  61. Mitrecic I52
  62. Bouchy Jacobsson ML53
  63. Bro Christensen A54
  64. Bodtger U55
  65. Meyer CN56
  66. Vestergaard Jensen A57
  67. Elsaid Abd Elwahhab I58
  68. Elsayed Morsy N59
  69. Shafiek H60
  70. Sobh E61
  71. Abdulsemed KA62
  72. Bertrand F63
  73. Brunbuisson C64
  74. De Montmollin E65
  75. Fartoukh M66
  76. Messika J67
  77. Tattevin P68
  78. Khoury A69
  79. Ebruke B70
  80. Dreher M71
  81. Kolditz M72
  82. Meisinger M73
  83. Pletz MW74
  84. Hagel S74
  85. Rupp J75
  86. Schaberg T76
  87. Spielmanns M77
  88. Creutz P78
  89. Suttorp N78
  90. Siawlartey B79
  91. Dimakou K80
  92. Papapetrou D81
  93. Tsigou E82
  94. Ampazis D82
  95. Kaimakamis E83
  96. Bhatia M84
  97. Dhar R85
  98. Dsouza G86
  99. Garg R87
  100. Koul PA88
  101. Jayaraj BS89
  102. Narayan KV90
  103. Udnur HB91
  104. Krishnamurthy SB91
  105. Kant S92
  106. Swarnakar R93
  107. Salvi S94
  108. Limaye S94
  109. Golshani K95
  110. Keatings VM96
  111. Martinloeches I97
  112. Maor Y98
  113. Strahilevitz J99
  114. Battaglia S100
  115. Carrabba M101
  116. Ceriana P102
  117. Confalonieri M103
  118. Darminio Monforte A104
  119. Del Prato B105
  120. De Rosa M106
  121. Fantini R107
  122. Fiorentino G108
  123. Gammino MA109
  124. Menzella F110
  125. Milani G111
  126. Nava S112
  127. Palmiero G113
  128. Petrino R114
  129. Gabrielli B114
  130. Rossi P115
  131. Sorino C116
  132. Steinhilber G117
  133. Zanforlin A118
  134. Franzetti F119
  135. Carone M120
  136. Patella V121
  137. Scarlata S122
  138. Comel A123
  139. Kurahashi K124
  140. Aoun Bacha Z125
  141. Barajas Ugalde D126
  142. Ceballos Zuniga O127
  143. Villegas JF128
  144. Medenica M129
  145. Van De Garde EMW130
  146. Raj Mihsra D131
  147. Shrestha P132
  148. Ridgeon E133
  149. Ishola Awokola B134
  150. Nwankwo ONO135
  151. Olufunlola AB136
  152. Olumide S137
  153. Ukwaja KN138
  154. Irfan M139
  155. Minarowski L140
  156. Szymon S141
  157. Froes F142
  158. Leuschner P143, 144
  159. Meireles M144
  160. Ferrao C144
  161. Neves J144
  162. Ravara SB145
  163. Brocovschii V147
  164. Ion C148
  165. Rusu D149
  166. Toma C150
  167. Chirita D151
  168. Dorobat CM152
  169. Birkun A153
  170. Kaluzhenina A154
  171. Almotairi A155
  172. Bukhary ZAA156
  173. Edathodu J157
  174. Fathy A158
  175. Mushira Abdulaziz Enani A159
  176. Eltayeb Mohamed N159
  177. Ulhadi Memon J160
  178. Bella A161
  179. Bogdanovic N162
  180. Milenkovic B163
  181. Pesut D164
  182. Borderias L165
  183. Bordon Garcia NM166
  184. Cabello Alarcon H167
  185. Cilloniz C168
  186. Torres A168
  187. Diazbrito V168
  188. Casas X168
  189. Encabo Gonzalez A169
  190. Fernandezalmira ML170
  191. Gallego M171, 224
  192. Gaspargarcia I172
  193. Gonzalez Del Castillo J173
  194. Javaloyes Victoria P174
  195. Laserna Martinez E175
  196. Malo De Molina R176
  197. Menendez R177
  198. Pandosandoval A178
  199. Prat Aymerich C179, 225
  200. Lacoma De La Torre A179, 225
  201. Garciaolive I179, 225
  202. Rello J180
  203. Moyano S180
  204. Sanz F181
  205. Sibila O182
  206. Rodrigotroyano A182
  207. Soleviolan J183
  208. Uranga A184
  209. Van Boven JFM185
  210. Vendrell Torra E186
  211. Pujol JA186
  212. Feldman C187
  213. Kee Yum H188
  214. Fiogbe AA189
  215. Yangui F190
  216. Bilaceroglu S191
  217. Dalar L192
  218. Yilmaz U193
  219. Bogomolov A194
  220. Elahi N195
  221. Dhasmana DJ196
  222. Feneley A197
  223. Hancock C198
  224. Hill AT199
  225. Rudran B200
  226. Ruizbuitrago S201
  227. Campbell M201
  228. Whitaker P202
  229. Youzguin A203
  230. Singanayagam A204
  231. Allen KS205
  232. Brito V206
  233. Dietz J207
  234. Dysart CE208, 226
  235. Kellie SM208, 226
  236. Francosadud RA209
  237. Meier G209
  238. Gaga M210
  239. Holland TL211
  240. Bergin SP211
  241. Kheir F212
  242. Landmeier M213
  243. Lois M214
  244. Nair GB215
  245. Patel H216
  246. Reyes K217
  247. Rodriguezcintron W218
  248. Saito S219
  249. Soni NJ220
  250. Noda J220
  251. Hinojosa CI220
  252. Levine SM220
  253. Angel LF220
  254. Anzueto A220
  255. Scott Whitlow K221
  256. Hipskind J221
  257. Sukhija K221
  258. Totten V221
  259. Wunderink RG222
  260. Shah RD222
  261. Mateyo KJ223
  262. Carugati M119
  263. Morosi M119
  264. Monge E119

Source: European Journal of Internal Medicine Published:2019


Abstract

Background: Who should be tested for viruses in patients with community acquired pneumonia (CAP), prevalence and risk factors for viral CAP are still debated. We evaluated the frequency of viral testing, virus prevalence, risk factors and treatment coverage with oseltamivir in patients admitted for CAP. Methods: Secondary analysis of GLIMP, an international, multicenter, point-prevalence study of hospitalized adults with CAP. Testing frequency, prevalence of viral CAP and treatment with oseltamivir were assessed among patients who underwent a viral swab. Univariate and multivariate analysis was used to evaluate risk factors. Results: 553 (14.9%) patients with CAP underwent nasal swab. Viral CAP was diagnosed in 157 (28.4%) patients. Influenza virus was isolated in 80.9% of cases. Testing frequency and viral CAP prevalence were inhomogeneous across the participating centers. Obesity (OR 1.59, 95%CI: 1.01–2.48; p = 0.043) and need for invasive mechanical ventilation (OR 1.62, 95%CI: 1.02–2.56; p = 0.040) were independently associated with viral CAP. Prevalence of empirical treatment with oseltamivir was 5.1%. Conclusion: In an international scenario, testing frequency for viruses in CAP is very low. The most common cause of viral CAP is Influenza virus. Obesity and need for invasive ventilation represent independent risk factors for viral CAP. Adherence to recommendations for treatment with oseltamivir is poor. © 2018 European Federation of Internal Medicine
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