Effect of Zinc Supplementation on Quality of Life and Sleep Quality in Young Women With Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial Publisher Pubmed



Jafari F¹ ; Tarrahi MJ² ; Farhang A¹ ; Amani R¹
Source: Archives of Gynecology and Obstetrics Published:2020

Abstract

Introduction: Premenstrual syndrome is a prevalent disorder affecting a large number of women in their reproductive ages. Nutritional importance of zinc has been known for a long time and studies have shown that zinc can positively affect psychological disorders. Purpose: The aim of this study was to evaluate the effects of zinc supplementation on quality of life and sleep quality of young women diagnosed with premenstrual syndrome. Methods: This randomized, double-blind, placebo-controlled trial was carried out on 60 young university women that were allocated into two groups of intervention who took 30 mg/day of elemental zinc or placebo for three months. Pre- and post-intervention, participants completed the questionnaires of quality of life and Pittsburgh sleep quality. Results: After supplementation, quality of life score in the intervention group was increased (+ 9.185 ± 7.29, P < 0.001), however, in comparison with the control group, results were not significant; Physical aspects of quality of life score were significantly enhanced (+ 5.55 ± 3.71 vs. + 0.13 ± 2.87, P < 0.001). Sleep quality was marginally improved just in the zinc group (− 1.48 ± 4.12, P = 0.07). Conclusion: Zinc supplementation for 12 weeks had beneficial effects on physical aspects of quality of life in young women with premenstrual syndrome. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.