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Electromagnetic Fields and Optomechanics in Cancer Diagnostics and Treatment Publisher Pubmed



Salari V1 ; Barzanjeh S2 ; Cifra M3 ; Simon C4, 5 ; Scholkmann F6, 7 ; Alirezaei Z8 ; Tuszynski JA9, 10
Authors
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Authors Affiliations
  1. 1. Department of Physics, Isfahan University of Technology, Isfahan, 84156-83111, Iran
  2. 2. Institute of Science and Technology (IST) Austria, Klosterneuburg, 3400, Austria
  3. 3. Institute of Photonics and Electronics, Czech Academy of Sciences, Chaberska 57, Prague, 182 00, Czech Republic
  4. 4. Department of Physics and Astronomy, University of Calgary, Calgary, T2N 1N4, AB, Canada
  5. 5. Institute for Quantum Science and Technology, University of Calgary, Calgary, T2N 1N4, AB, Canada
  6. 6. Biomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, CH-8091, Switzerland
  7. 7. Research Office for Complex Physical and Biological Systems (ROCoS), Zurich, CH-8038, Switzerland
  8. 8. Department of Medical Physics, Isfahan University of Medical Sciences, Isfahan, Iran
  9. 9. Department of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, T6G 1Z2, AB, Canada
  10. 10. Department of Physics, University of Alberta, Edmonton, T6G 2E1, AB, Canada

Source: Frontiers in Bioscience - Landmark Published:2018


Abstract

In this paper, we discuss biological effects of electromagnetic (EM) fields in the context of cancer biology. In particular, we review the nanomechanical properties of microtubules (MTs), the latter being one of the most successful targets for cancer therapy. We propose an investigation on the coupling of electromagnetic radiation to mechanical vibrations of MTs as an important basis for biological and medical applications. In our opinion, optomechanical methods can accurately monitor and control the mechanical properties of isolated MTs in a liquid environment. Consequently, studying nanomechanical properties of MTs may give useful information for future applications to diagnostic and therapeutic technologies involving non-invasive externally applied physical fields. For example, electromagnetic fields or high intensity ultrasound can be used therapeutically avoiding harmful side effects of chemotherapeutic agents or classical radiation therapy. © 2018 Frontiers in Bioscience. All rights reserved.
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