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Retinal and Choroidal Thickness in Fuchs Uveitis Syndrome: A Contralateral Eye Study Publisher Pubmed



Kianersi F1 ; Taheri A1 ; Mirmohammadkhani M2, 3 ; Akhlaghi M1 ; Peyman A1 ; Kianersi H1 ; Irajpour M1 ; Kianersi H1 ; Pourazizi M1
Authors
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Authors Affiliations
  1. 1. Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran
  3. 3. Department of Epidemiology and Biostatistics, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran
  4. 4. Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran

Source: BMC Ophthalmology Published:2024


Abstract

Background: To investigate the subfoveal retinal and choroidal thickness in patients with unilateral Fuchs Uveitis Syndrome (FUS). Methods: This comparative contralateral study was performed in affected eyes with FUS versus fellow eyes. For each eye parameters such as subfoveal choroidal thickness (SCT), subfoveal choriocapillary thickness (SCCT), central macular thickness (CMT), and central macular volume (CMV) were measured; then the measured values of affected and fellow unaffected eye were compared. Results: Thirty-seven patients (74 eyes) including 19 females (51.4%) with a mean age of 36.9 ± 7.6 years were enrolled. The mean SCT was lower in the affected eyes (344.51 ± 91.67) than in the fellow (375.59 ± 87.33) with adjusting for duration of disease and axial lengths (P < 0.001). The mean SCCT, CMT, and CMV were higher in eyes with FUS than in fellow eyes (P < 0.05). Conclusions: The result of our study demonstrated that affected eyes in patients with FUS tend to have thinner SCT and thicker SCCT and CMT compared to uninvolved fellow eyes. © The Author(s) 2024.
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