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A Case Report of Ethambutol Toxic Optic Atrophy



Naderian G1 ; Fesharaki H1 ; Ghoraishi M1 ; Sajjadi V2
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Authors Affiliations
  1. 1. Feiz Ophthalmology Center, Isfahan University of Medical Sciences, Iran
  2. 2. Ophthalmology Clinic, Iran

Source: Journal of Isfahan Medical School Published:2007

Abstract

Background: In this paper, we present a case with acute vision loss due to ethambutol therapy. A sixty-three year-old man underwent tuberculosis treatment (Ethambutol, Izoniazid, Rifampicin, Pirazin Amid) six years before this report. Acute bilateral vision loss occurred three months later while receiving ethambutol treatment. Total vision loss in one eye, and partial vision loss in another eye and optic atrophy were found on physical and neurological examinations. Ethambutol is one of the major drugs in tuberculosis treatment. It is usually well tolerated; however an Important side effect of this drug is retro bulbar optic neuropathy, which should be considered. © 2007, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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