Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs

Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs Publisher

Summary: Does platelet-rich fibrin boost orthodontic bone remodeling? A dog study found no significant differences versus controls despite several measured changes. #Orthodontics #BoneHealth

Tabibi A ; Feizbakhsh M ; Esnaashari N ; Razavi S M

Source: Dental Research Journal Published:2023

Abstract

Background: – This study aimed to assess the effect of local injection of injectable platelet-rich fibrin (i-PRF) on bone remodeling during orthodontic tooth movement in dogs. Materials and Methods: – In this animal study, the maxillary first premolars of four adult male mixed-breed dogs were bilaterally extracted, and a nickel–titanium closed coil spring with 150 g force was placed between the canine and second premolar teeth. One quadrant of the maxilla was randomly selected as the test quadrant, and 0.5 cc i-PRF was injected into the periodontal ligament (PDL) around the second premolar at 1, 21, and 42 days. The other quadrant served as the control group and received saline injections. The dogs were sacrificed after 63 days, histological sections were prepared, and changes in bone remodeling were assessed by comparing the percentage of osteogenesis and number of osteoblasts and osteoclasts between the two groups by the Wilcoxon and Mann–Whitney U-tests (a = 0.05). Results: – The percentage of osteogenesis (16.0% ± 4.96% in i-PRF and 13.5% ± 4.43% in the control), the percentage of newly formed lamellar bone (10.25% ± 2.87% in i-PRF and 8.75% ± 2.36% in the control), the percentage of woven bone (5.75% ± 2.21% in i-PRF and 4.75% ± 2.36% in the control), the number of osteoblasts (15.0 ± 3.46 in i-PRF and 11.75 ± 2.36 in the control), and the number of osteoclasts (11.25 ± 4.34 in i-PRF and 6.25 ± 2.62 in the control) were not significantly different between the two groups (P > 0.05). Conclusion: – PDL injection of i-PRF around the second premolars of dogs under orthodontic force had no significant effect on bone remodeling. Copyright: © 2023 Dental Research Journal

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Style	Citing Format
MLA	Tabibi A, et al.. "Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs." Dental Research Journal, vol. 20, no. 1, 2023, pp. -.
APA	Tabibi A, Feizbakhsh M, Esnaashari N, Razavi S M (2023). Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs. Dental Research Journal, 20(1), -.
Chicago	Tabibi A, Feizbakhsh M, Esnaashari N, Razavi S M. "Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs." Dental Research Journal 20, no. 1 (2023): -.
Harvard	Tabibi A et al. (2023) 'Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs', Dental Research Journal, 20(1), pp. -.
Vancouver	Tabibi A, Feizbakhsh M, Esnaashari N, Razavi S M. Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs. Dental Research Journal. 2023;20(1):-.
BibTex	@article{ author = {Tabibi A and Feizbakhsh M and Esnaashari N and Razavi S M}, title = {Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs}, journal = {Dental Research Journal}, volume = {20}, number = {1}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Tabibi A AU - Feizbakhsh M AU - Esnaashari N AU - Razavi S M TI - Effect of Local Injection of Injectable Platelet-Rich Fibrin on Bone Remodeling During Orthodontic Tooth Movement in Dogs JO - Dental Research Journal VL - 20 IS - 1 SP - EP - PY - 2023 ER -

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