Comparison of the Therapeutic Effects of 5% Minoxidil Solution Alone With the Medicinal Combination of 5% Minoxidil and 0.005% Latanoprost in Men With Androgenetic Alopecia Referred to Skin Clinics of Isfahan University of Medical Sciences; [مقایسهی اثرات درمانی محلول ماینوکسیدیل 5 % به تنهایی با ترکیب دارویی ماینوکسیدیل 5 % و لاتانوپروست 005 / 0 % در مردان مبتلا به آلوپسی آندروژنتیک مراجعهکننده به درمانگاههای پوست دانشگاه علوم پزشکی اصفهان] Publisher



Poostiyan N^{1, 2, 3} ; Faghihi G^{1, 2, 3} ; Poostiyan E^{1, 2, 3} ; Bagherkamareh A⁴ ; Sindarreh S⁵
Source: Journal of Isfahan Medical School Published:2024

Abstract

Background: This study aims to investigate and compare the therapeutic effects of 5% minoxidil solution alone with the combination of 5% minoxidil and 0.005% latanoprost in men with androgenetic alopecia referred to skin clinics of Isfahan University of Medical Sciences. Methods: This study was a randomized, double-blind clinical trial on 50 male patients with androgenetic alopecia at Al-Zahra Hospital and Sediqeh Tahereh Center in Isfahan. Participants were randomly assigned to two groups of 25 people: one receiving minoxidil 5% and the other receiving a combination of latanoprost 0.005% and minoxidil 5%. Outcomes measured included patient improvement, hair loss reduction, hair growth increase, and patient satisfaction. Findings: A total of 45 participants, with a mean age of 29.1+12.5 years, were studied. N Groups did not show significant differences in age, duration of illness, or percentage of head involvement. Treatment recovery rate, satisfaction, and drug side effects (peeling, erythema, hair loss, and itching) showed no significant differences between the two groups. Conclusion: Generally, the present study showed no significant difference between the rate of recovery, satisfaction, and complications after treatment in both intervention groups of minoxidil 5% and the drug combination of latanoprost 0.005% and minoxidil 5%. © 2024 Isfahan University of Medical Sciences(IUMS). All rights reserved.