Possibility of Post Percutaneous Nephrolithotomy Renal Function Alterations Leading to Acute Kidney Injury Publisher



Rahbar M¹ ; Karimian B² ; Kazemi R³ ; Esfahanian F⁴ ; Oliveira Reis L⁵ ; Zia H⁶ ; Khajavi A⁷ ; Guitynavard F⁸ Show Affiliations
Source: Translational Research in Urology Published:2023

Abstract

Introduction Percutaneous nephrolithotomy has obtained the mainstay role as a procedure of gold standard in patients harboring renal lithiasis larger than 2 cm. It has earned an outstanding reputation as a low complications/low mortality minimally-invasive procedure worldwide. Therefore, its complications carry a great deal, and considering bleeding as its main problem, possible post-bleeding Acute Renal Injury must be checked out. Methods This is a cross-sectional study planned for 91 patients who underwent PCNL. The renal Function variable had been tuned primarily as Serum Creatinine levels, which had been obtained before surgery following afterwards sessions as the order of days 1, 2, and 30 after surgery. Results Demographic data were as Gender: 63(69.2%) males. The mean age of the patients was 47.8± 4.7 years. Analytic Data as Mean stone size was 25 mm, Serum sodium & potassium & hemoglobin & hematocrit level &GFR. Data analysis uttered the considerable rise in the creatinine levels on the second day (p value<0.05), although respecting its levels after 1 month, all recovered in one month and meant no considerable decline neither in GFR or other biochemical levels. Conclusions Our Data revealed a considerable decrease in the overall kidney function through an increase in the serum creatinine and electrolytes levels on the second postoperative day which was shown to be completely recovered based on their measured levels after one month. © 2023 Urology Research Center (URC).