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Schizophrenia and Macroprolactinoma: Is There a Deep Link? Publisher



Bamarinejad A1 ; Nasiri S1 ; Bamarinejad F1 ; Salehidoost R1 ; Zarefarashbandi E1, 2
Authors

Source: Advanced Biomedical Research Published:2020


Abstract

Prolactinomas are the most common type of functional pituitary tumors. Dopamine agonists is the most important drugs used in prolactinoma,have antagonistic effect with antipsychotic drugs used in schizophrenia. Conversely, dopamine antagonist drugs increase prolactin in patients with simultaneous schizophrenia. In the present case, we report a 29-year-old single male with schizophrenia who treated for 8 years with risperidone and presented with macroprolactinoma. Iatrogenic hyperprolactinemia is a well-known side effect of dopamine antagonist drugs for treatment in a patient with schizophrenia. On the other hand, it appears these drugs have the other side effects, such as drug- induced prolactinoma or boost growth. © 2020 Advanced Biomedical Research | Published by Wolters Kluwer - Medknow.