Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Hepatic Myxosarcoma in a Domestic Shorthair Cat Publisher Pubmed



Moosavian H1 ; Ghiassi R2 ; Izadi SS3 ; Almasi P1 ; Vahabi R4 ; Fazli M5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Iran
  2. 2. Department of clinical sciences, faculty of veterinary medicine, Garmsar Branch, Islamic Azad University, Iran
  3. 3. Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Iran
  4. 4. Department of Pathology and Laboratory Medicine, Isfahan University of Medical Sciences, Iran
  5. 5. Department of Biology, Faculty of Basic Science, Islamic Azad University, Iran

Source: Journal of the South African Veterinary Association Published:2023


Abstract

Myxosarcomas are rare malignant neoplasms of soft connective tissues, and there are no reports of hepatic myxosarcomas in cats. An eight-year-old male, neutered, domestic shorthair cat presented with progressive hyporexia, lethargy, and weight loss. An ultrasonography study showed a large abdominal mass connected to the liver. The cat underwent a laparotomy and the mass was removed. Histopathological evaluation of the mass supported the diagnosis of a myxosarcoma. Tumour cells were positive with vimentin and alcian blue stain, and negative with PAS, pan-cytokeratin, s100, epithelial membrane antigen, and α-smooth muscle actin. The Ki-67 index by immunohistochemistry was 6%. The cat was euthanased due to severe lethargy and recumbency. Myxoid soft tissue neoplasms are very rare in cats, and to the best of our knowledge, this is the first report of a hepatic myxosarcoma in a cat. In the present case, the diagnosis was made based on histopathological and immunohistochemical findings and an alcian blue-positive supporting matrix. © 2023 The Author(s)
Related Docs
Experts (# of related papers)