Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites

Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites Publisher

Haghighat M¹ ; Honar N¹ ; Imanieh MH¹ ; Ataollahi M¹ ; Dehghani SM¹ ; Shahramian I¹ ; Karbasian F¹ ; Fard HK² ; Soheili M³ ; Mortazavi SMM¹

Source: Medical Journal of the Islamic Republic of Iran Published:2023

Abstract

Background: Large-volume paracentesis has become the first treatment choice for patients with severe and refractory ascites. The studies have reported several complications after therapeutic paracentesis. But there are few published data on the complications with or without Albumin therapy. We aimed to analyze the safety and complications of large-volume paracentesis in children with or without albumin therapy. Methods: This study was conducted on children with severe ascites with chronic liver disease who underwent large-volume paracentesis. They were divided into albumin-infused and albumin non-infused groups. In the case of coagulopathy, no adjustment was made. Albumin was not administered after the procedure. The outcomes were monitored to evaluate the complications. To compare two groups, a t-test was utilized, and the ANOVA test was used to compare several groups. If the requirements for using these tests were not met, Mann-Whitney and Kruskal-Wallis tests were applied. Results: Decreased heart rate was observed in all time intervals and was meaningful six days after paracentesis. MAP also decreased statistically at 48 hours and six days after the procedure (P < 0.05). Other variables did not show any meaningful change. Conclusion: Children having tense ascites with thrombocytopenia, prolonged PT, Child-Pugh class C, and encephalopathy can undergo large-volume paracentesis without any complication. Albumin administration before the procedure in patients with low levels of Albumin (<2.9) can effectively overcome the problems of tachycardia and increased mean arterial pressure. There will be no need for Albumin administration after paracentesis. © Iran University of Medical Sciences

Style	Citing Format
MLA	Haghighat M, et al.. "Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites." Medical Journal of the Islamic Republic of Iran, vol. 37, no. 1, 2023, pp. -.
APA	Haghighat M, Honar N, Imanieh MH, Ataollahi M, Dehghani SM, Shahramian I, Karbasian F, Fard HK, Soheili M, Mortazavi SMM (2023). Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites. Medical Journal of the Islamic Republic of Iran, 37(1), -.
Chicago	Haghighat M, Honar N, Imanieh MH, Ataollahi M, Dehghani SM, Shahramian I, Karbasian F, Fard HK, Soheili M, Mortazavi SMM. "Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites." Medical Journal of the Islamic Republic of Iran 37, no. 1 (2023): -.
Harvard	Haghighat M et al. (2023) 'Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites', Medical Journal of the Islamic Republic of Iran, 37(1), pp. -.
Vancouver	Haghighat M, Honar N, Imanieh MH, Ataollahi M, Dehghani SM, Shahramian I, et al.. Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites. Medical Journal of the Islamic Republic of Iran. 2023;37(1):-.
BibTex	@article{ author = {Haghighat M and Honar N and Imanieh MH and Ataollahi M and Dehghani SM and Shahramian I and Karbasian F and Fard HK and Soheili M and Mortazavi SMM}, title = {Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites}, journal = {Medical Journal of the Islamic Republic of Iran}, volume = {37}, number = {1}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Haghighat M AU - Honar N AU - Imanieh MH AU - Ataollahi M AU - Dehghani SM AU - Shahramian I AU - Karbasian F AU - Fard HK AU - Soheili M AU - Mortazavi SMM TI - Evaluation of Outcomes and Complications of Large Volume Paracentesis Without Albumin and Coagulopathy Therapy in Pediatrics With Severe Ascites JO - Medical Journal of the Islamic Republic of Iran VL - 37 IS - 1 SP - EP - PY - 2023 ER -

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