Tehran University of Medical Sciences

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Faculty Members have conducted research related to the The Possible Effect of Microrna-155 (Mir-155) and Bace1 Inhibitors in the Memory of Patients With Down Syndrome and Alzheimer's Disease: Design, Synthesis, Virtual Screening, Molecular Modeling and Biological Evaluations
Alireza Biglari
Alireza Biglari

Professor of Genetics

Department Medical Genetics

School of Medicine

Tehran University of Medical Sciences

All Documents
1. A Novel Homozygous Variant (C.5876T > C: P. Leu1959pro) in Dysf Segregates With Limb-Girdle Muscular Dystrophy: A Case Report, BMC Musculoskeletal Disorders (2024)
2. A Novel Nanobody-Based Immunocytokine of a Mutant Interleukin-2 As a Potential Cancer Therapeutic, AMB Express (2024)
3. Catecholaminergic Polymorphic Ventricular Tachycardia (And Seizure) Caused by a Novel Homozygous Likely Pathogenic Variant in Casq2 Gene, Gene (2024)
4. Comparative Assessment of a Covid-19 Vaccine After Technology Transfer to Iran From Critical Quality Attributes to Clinical and Immunogenicity Aspects, Scientific Reports (2024)
5. Lessons From Covid-19 Pandemic: A Successful Policy and Practice by Pasteur Institute of Iran, Iranian biomedical journal (2024)
6. Efficacy and Safety of a Protein-Based Sars-Cov-2 Vaccine: A Randomized Clinical Trial, JAMA Network Open (2023)
7. Efficacy and Safety of a Protein-Based Sars-Cov-2 Vaccine: A Randomized Clinical Trial, JAMA Network Open (2023)
8. Evaluation of Pastocovac Plus Vaccine As a Booster Dose on Vaccinated Individuals With Inactivated Covid-19 Vaccine, Heliyon (2023)
9. Immunogenicity and Safety of Heterologous Boost Immunization With Pastocovac Plus Against Covid-19 in Chadox1-S or Bbibp-Corv Primed Individuals, PLoS Pathogens (2023)
10. Investigating the Motivations and Barriers of People's Participation in the Vaccination Program Against Covid19 Disease in Semnan City in 1400-A Qualitative Study, Koomesh (2023)
11. Looking for Biomarkers in Interferon Response Pathway to Predict Response to Oncolytic Hsv-1 in Breast Cancer: An Ex Vivo Study, Cancer Biomarkers (2023)
12. No Association of As3mt Gene Polymorphisms With Susceptibility to Hepatotoxicity and in Apl Patients Treated With As2o3: A Single Center Study, International Journal of Hematology-Oncology and Stem Cell Research (2023)
13. Pastocovac and Pastocovac Plus As Protein Subunit Covid-19 Vaccines Led to Great Humoral Immune Responses in Bbip-Corv Immunized Individuals, Scientific Reports (2023)
14. Three Doses of a Recombinant Conjugated Sars-Cov-2 Vaccine Early After Allogeneic Hematopoietic Stem Cell Transplantation: Predicting Indicators of a High Serologic Response—A Prospective, Single-Arm Study, Frontiers in Immunology (2023)
15. Human Il-2Rɑ Subunit Binding Modulation of Il-2 Through a Decline in Electrostatic Interactions: A Computational and Experimental Approach, PloS one (2022)
16. Human Il-2Rα Subunit Binding Modulation of Il-2 Through a Decline in Electrostatic Interactions: A Computational and Experimental Approach, PLoS ONE (2022)
17. Kh Domain Containing 3 Like (Khdc3l) Frame-Shift Mutation Causes Both Recurrent Pregnancy Loss and Hydatidiform Mole, European Journal of Obstetrics and Gynecology and Reproductive Biology (2021)
18. A Novel Non-Frameshift Ada Deletion Detected by Whole Exome Sequencing in an Iranian Family With Severe Combined Immunodeficiency, Iranian Journal of Allergy# Asthma and Immunology (2020)
19. Exome-First Approach Identified Novel Homozygous Dedicator of Cytokinesis 8 (Dock8) Mutations in Three Unrelated Iranian Pedigrees Suspected With Hyper-Ige Syndrome, Iranian Journal of Allergy, Asthma and Immunology (2020)
20. While Urine and Plasma Decorin Remain Unchanged in Prostate Cancer, Prostatic Tissue Decorin Has a Prognostic Value, Iranian Biomedical Journal (2020)
21. Evaluation of Exosomal Mir-9 and Mir-155 Targeting Pten and Dusp14 in Highly Metastatic Breast Cancer and Their Effect on Low Metastatic Cells, Journal of Cellular Biochemistry (2019)
22. Exosomal Mirnas From Highly Metastatic Cells Can Induce Metastasis in Non-Metastatic Cells, Life Sciences (2019)
23. Expression Level of Circulating Cell Free Mir-155 Gene in Serum of Patients With Diabetic Nephropathy, Clinical Laboratory (2019)
24. Whole Exome Sequencing Revealed a Novel Gjb1 Pathogenic Variant and a Rare Bscl2 Mutation in Two Iranian Large Pedigrees With Multiple Affected Cases of Charcot-Marie-Tooth, International Journal of Molecular and Cellular Medicine (2019)
25. Expression Level of Circulating Mir-93 in Serum of Patients With Diabetic Nephropathy; [Diyabetik Nefropati Hastalarinin Serumlarinda Serbest Mir-93 Ekspresyon Duzeyleri], Turkish Journal of Endocrinology and Metabolism (2018)
26. Recombinant Fibromodulin Has Therapeutic Effects on Diabetic Nephropathy by Down-Regulating Transforming Growth Factor-Β1 in Streptozotocin-Induced Diabetic Rat Model, Iranian Journal of Basic Medical Sciences (2016)