Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Evaluation of Targetable Biomarkers for Chimeric Antigen Receptor T-Cell (Car-T) in the Treatment of Pancreatic Cancer: A Systematic Review and Meta-Analysis of Preclinical Studies : Pancreatic Cancer Is One of the Lethal Malignant Tumours in the World. in This Study, We Investigated the Car T-Cell Therapy of Pancreatic Cancer
Ali Akbar Amirzargar
Ali Akbar Amirzargar

Professor of Medical Immunology

Department Immunology

School of Medicine

Molecular Immunology Research Center

Tehran University of Medical Sciences

All Documents
1. Talabostat, Fibroblast Activation Protein Inhibitor, Attenuates Inflammation and Fibrosis in Systemic Sclerosis, Inflammopharmacology (2024)
2. Blood Regulatory T Cells in Inflammatory Bowel Disease, a Systematic Review, and Meta-Analysis, International Immunopharmacology (2023)
3. Hla Study in Iranian Desert Yazd Province Inhabitants, Human Immunology (2023)
4. Investigating the Relationship Between the Number and Activity of Natural Killer Cells With Increased Cytomegalovirus and Cmv Disease After Kidney Transplantation, Transplant Immunology (2023)
5. Isolation and in Vitro Expansion of Regulatory T Cells From Β-Thalassemia Major Kids and in Vitro Evaluation of Their Plasticity and Inhibitory Effects in the Presence of Pro-Inflammatory Cytokines, International Archives of Allergy and Immunology (2023)
6. Potential Roles of Inflammasomes in the Pathophysiology of Psoriasis: A Comprehensive Review, Molecular Immunology (2023)
7. The Impact of Killer Cell Immunoglobulin-Like Receptor (Kir) Genes and Human Leukocyte Antigen (Hla) Class I Ligands on Predisposition or Protection Against Prostate Cancer, Immunobiology (2023)
8. Tumor Necrosis Factor-Α (-308G>A) Gene Polymorphism and Its Association With Asthma and Atopy Status, Iranian Journal of Allergy# Asthma and Immunology (2023)
9. Association Between Human Leukocyte Antigens and Cutaneous Adverse Drug Reactions to Antiepileptics and Antibiotics in the Iranian Population, Dermatologic Therapy (2022)
10. Frequency of Cd39+, Lag3+, and Ctla4+ Regulatory T Cells in Two Different Immunosuppressive Protocols in Renal Allograft Recipients (Sirolimus Vs Mycophenolate Mofetil): A Cohort Report, Iranian Journal of Immunology (2022)
11. Hla Alleles and Haplotypes in Iran Tabriz Azeris Population: Genes and Languages Do Not Correlate, Human Immunology (2022)
12. Hla Genetic Study in Iran Saqqez-Baneh Kurds: No Genetic Trace of Aryan Invasions in Anatolian Turks and Kurds Is Found, Human Immunology (2022)
13. Natural Killer Cells and Killer Cell Immunoglobulin-Like Receptors in Solid Organ Transplantation: Protectors or Opponents?, Transplantation Reviews (2022)
14. Potential Roles of Long Noncoding Rnas As Therapeutic Targets in Organ Transplantation, Frontiers in Immunology (2022)
15. Safety and Immunogenicity of an Inactivated Virus Particle Vaccine for Sars-Cov-2, Biv1-Coviran: Findings From Double-Blind, Randomised, Placebo-Controlled, Phase I and Ii Clinical Trials Among Healthy Adults, BMJ Open (2022)
16. The Efficacy of a New Protocol of Oral Immunotherapy to Wheat for Desensitization and Induction of Tolerance, Iranian Journal of Allergy# Asthma and Immunology (2022)
17. Upregulation of Unfolded Protein Response and Er Stress–Related Il-23 Production in M1 Macrophages From Ankylosing Spondylitis Patients, Inflammation (2022)
18. Association of Hla Class Ii Alleles With Disease Severity and Treatment Response in Iranian Patients With Myasthenia Gravis, Journal of Neuromuscular Diseases (2021)
19. Association of Il-15 and Ip-10 Serum Levels With Cytomegalovirus Infection, Cmv Viral Load and Cyclosporine Level After Kidney Transplantation, Reports of Biochemistry and Molecular Biology (2021)
20. Cell Therapy in Transplantation: A Comprehensive Review of the Current Applications of Cell Therapy in Transplant Patients With the Focus on Tregs, Car Tregs, and Mesenchymal Stem Cells, International Immunopharmacology (2021)
21. Evaluation of Thymic Output and Regulatory T Cells in Kidney Transplant Recipients With Chronic Antibody-Mediated Rejection, BioMed Research International (2021)
22. Hcv Core/Ns3 Protein Immunization With “N-Terminal Heat Shock Gp96 Protein (Rnt (Gp96))” Induced Strong and Sustained Th1-Type Cytokines in Immunized Mice, Vaccines (2021)
23. Investigating the Role of Baff and Its Receptors in Renal Transplant Recipients With Chronic Antibody-Mediated Rejection, Journal of Immunology Research (2021)
24. Serological and Molecular Tests for Covid-19: A Recent Update, Iranian Journal of Immunology (2021)
25. B Cell Modulation Strategies in the Improvement of Transplantation Outcomes, Molecular Immunology (2020)
26. Frequency of Dendritic Cell Subsets and Ilt3, Ilt4 Gene Expression in Two Different Immunosuppressive Protocols in Kidney Transplant Recipients. a Cohort Report, Molecular Biology Reports (2020)
27. Gene Expression and Levels of Tgf-Β in Pbmc Is Associated With Severity of Symptoms in Chronic Heart Failure, Avicenna Journal of Medical Biotechnology (2020)
28. Gorgan (Iran) Population Hla Genetics and Anthropology, Human Immunology (2020)
29. Human Leukocyte Antigen Class I (A, B) and Class Ii (Drb1) Allele and Haplotype Frequencies in Iranian Patients With Buerger's Disease, Immunity# Inflammation and Disease (2020)
30. Il-27 and Autoimmune Rheumatologic Diseases: The Good, the Bad, and the Ugly, International Immunopharmacology (2020)
31. Immunogenetics of Cancer, Cancer Immunology: A Translational Medicine Context# Second Edition (2020)
32. Intravenous Immunoglobulin Therapy in Myocarditis, Iranian Journal of Allergy# Asthma and Immunology (2020)
33. Transitional Immature Regulatory B Cells and Regulatory Cytokines Can Discriminate Chronic Antibody-Mediated Rejection From Stable Graft Function, International Immunopharmacology (2020)
34. A Dna Vaccine Expressing Fusion Protein E2-Nt(Gp96) Induces Hepatitis C Virus Cross-Neutralizing Antibody in Balb/C Mice, Hepatitis Monthly (2019)
35. Association Study of Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 and 2 Genes in Iranian Women With Preeclampsia, Iranian Journal of Public Health (2019)
36. Dynamic Variation of Kidney Injury Molecule-1 Mrna and Protein Expression in Blood and Urine of Renal Transplant Recipients: A Cohort Study, Clinical and Experimental Nephrology (2019)
37. Dysregulated Expression of Tim-3 and Nkp30 Receptors on Nk Cells of Patients With Chronic Lymphocytic Leukemia, Oncology Research and Treatment (2019)
38. Interleukin-10 and Transforming Growth Factor Beta1 Gene Polymorphisms in Chronic Heart Failure, Acta Biomedica (2019)
39. Natural Killer Cells Exhibit an Activated Phenotype in Peripheral Blood Mononuclear Cells of Renal Allograft Rejection Recipients: A Preliminary Study, Experimental and Clinical Transplantation (2019)
40. Sequential Monitoring of Tim-3 Mrna Expression in Blood and Urine Samples of Renal Transplant Recipients, Transplant Immunology (2019)
41. Sirolimus Vs Mycophenolate Moftile in Tacrolimus Based Therapy Following Induction With Antithymocyte Globulin Promotes Regulatory T Cell Expansion and Inhibits Rorγt and T-Bet Expression in Kidney Transplantation, Human Immunology (2019)
42. Th1, Th2, Th17 Cell Subsets in Two Different Immunosuppressive Protocols in Renal Allograft Recipients (Sirolimus Vs Mycophenolate Mofetil): A Cohort Study, International Immunopharmacology (2019)
43. The Prevalence of Brucellosis in Different Provinces of Iran During 2013-2015, Iranian Journal of Public Health (2019)
44. Tim Family Gene Polymorphism and Susceptibility to Rheumatoid Arthritis: Systematic Review and Meta-Analysis, PLoS ONE (2019)
45. Tlr-2, Tlr-4 and Myd88 Genes Expression in Renal Transplant Acute and Chronic Rejections, International Journal of Immunogenetics (2019)
46. Association Between Tlr2, Tlr4, and Cd14 Gene Polymorphisms and Acute Rejection in Kidney Transplant, Experimental and Clinical Transplantation (2018)
47. Association of Levels of Interleukin 17 and T-Helper 17 Count With Symptom Severity and Etiology of Chronic Heart Failure: A Case-Control Study, Croatian Medical Journal (2018)
48. Expression Patterns of Toll Like Receptor (Tlr)-2, Tlr-4 and Myeloid Differentiation Primary Response Gene 88 (Myd88) in Renal Transplant Patients Developing Allograft Dysfunction; a Cohort Study, Transplant Immunology (2018)
49. Gene Expression and Levels of Il-6 and Tnfα in Pbmcs Correlate With Severity and Functional Class in Patients With Chronic Heart Failure, Irish Journal of Medical Science (2018)
50. High Expression of Foxp3 Mrna in Blood and Urine As a Predictive Marker in Kidney Transplantation, Progress in Transplantation (2018)
51. Hla Class I and Class Ii Genes Distribution of the Sistanis in Iran, Iranian Journal of Immunology (2018)
52. Increased Levels of Il-23 in Peripheral Blood Mononuclear Cells of Patients With Chronic Heart Failure, Acta Medica Iranica (2018)
53. Interferon Regulatory Factors: Where to Stand in Transplantation, Transplant Immunology (2018)
54. Interleukin-2 and Interferon-Gamma Single Nucleotide Polymorphisms in Iranian Patients With Chronic Heart Failure, Avicenna Journal of Medical Biotechnology (2018)
55. Sicam-1, Svcam-1 and Se-Selectin Levels in Type 1 Diabetes, Fetal and Pediatric Pathology (2018)
56. Single Nucleotide Polymorphisms of the Genes Encoding Il-10 and Tgf-Β1 in Iranian Children With Atopic Dermatitis, Allergologia et Immunopathologia (2018)
57. The Impact of Donor and Recipient Kir Genes and Kir Ligands on the Occurrence of Acute Graft-Versus-Host Disease and Graft Survival After Hla-Identical Sibling Hematopoietic Stem Cell Transplantation, Turkish Journal of Medical Sciences (2018)
58. Toll-Like Receptor 4 in Renal Transplant, Experimental and Clinical Transplantation (2018)
59. Tumor Necrosis Factor-Alpha and Interleukin-6 Gene Polymorphisms in Iranian Patients With Ischemic Heart Failure, Avicenna Journal of Medical Biotechnology (2018)
60. Ankylosing Spondylitis M-Csf-Derived Macrophages Are Undergoing Unfolded Protein Response (Upr) and Express Higher Levels of Interleukin-23, Modern Rheumatology (2017)
61. Association of Human Leukocyte Antigens Class I & Ii With Graves’ Disease in Iranian Population, Iranian Journal of Immunology (2017)
62. Comparative Study of Substance P and Neurokinin a in Gingival Crevicular Fluid of Healthy and Painful Carious Permanent Teeth, Dental Research Journal (2017)
63. Enzyme-Linked Immunosorbent Spot (Elispot) Monitoring of Cytokine-Producing Cells for the Prediction of Acute Rejection in Renal Transplant Patients, European Cytokine Network (2017)
64. Foxp3, Rorγt and Il-10 Cytokine Profile in Chronic Heart Failure, Bratislava Medical Journal (2017)
65. High Expression of Tim-3 and Kim-1 in Blood and Urine of Renal Allograft Rejection Patients, Transplant Immunology (2017)
66. Hla-Drb1, Dqb1 Allele Frequencies in Iranian Patients (Sistani Ethnic) With Tuberculosis and Healthy Control, Tehran University Medical Journal (2017)
67. Human Leukocyte Antigen (Hla) Class I and Ii Polymorphism in Iranian Healthy Population From Yazd Province, Iranian Journal of Allergy# Asthma and Immunology (2017)
68. Increased Expression of Toll-Like Receptors 2 and 4 in Renal Transplant Recipients That Develop Allograft Dysfunction: A Cohort Study, Iranian Journal of Immunology (2017)
69. Investigation of Killer Immunoglobulin-Like Receptor (Kir) and Hla Genotypes to Predict the Occurrence of Acute Allograft Rejection After Kidney Transplantation, Iranian Journal of Allergy# Asthma and Immunology (2017)
70. Promoter Hypermethylation of Bcl11b Gene Correlates With Downregulation of Gene Transcription in Ankylosing Spondylitis Patients, Genes and Immunity (2017)
71. Ptpn22 Single-Nucleotide Polymorphisms in Iranian Patients With Type 1 Diabetes Mellitus, Immunological Investigations (2017)
72. Single Nucleotide Polymorphisms of Il-2, But Not Il-12 and Ifn-Γ, Are Associated With Increased Susceptibility to Chronic Spontaneous Urticaria, Allergologia et Immunopathologia (2017)
73. Analysis of Killer Cell Immunoglobulin-Like Receptor Genes and Their Hla Ligands in Iranian Patients With Ankylosing Spondylitis, Iranian Journal of Allergy# Asthma and Immunology (2016)
74. Association of Interleukin 1 Gene Cluster and Interleukin 1 Receptor Gene Polymorphisms With Ischemic Heart Failure, Bratislava Medical Journal (2016)
75. Effect of Tnf-Α Blockade in Gingival Crevicular Fluid on Periodontal Condition of Patients With Rheumatoid Arthritis, Iranian Journal of Immunology (2016)
76. Gene Polymorphisms of Interleukin-10 and Transforming Growth Factor Beta in Allergic Rhinitis, Allergologia et Immunopathologia (2016)
77. Il23r Gene Polymorphism With Juvenile Idiopathic Arthritis and Its Association With Serum Il-17A, International Journal of Rheumatic Diseases (2016)
78. Increased Levels of Cd4+ and Cd8+ T Cells Expressing Ccr1 in Patients Developing Allograft Dysfunction; a Cohort Study, Transplant Immunology (2016)
79. Lack of Association Between Interleukin-12 Gene Polymorphisms and Recurrent Aphthous Stomatitis, Avicenna Journal of Medical Biotechnology (2016)
80. Natural Killer Cell Subsets and Il-2, Il-15, and Il-18 Genes Expressions in Chronic Kidney Allograft Dysfunction and Graft Function in Kidney Allograft Recipients, International Journal of Organ Transplantation Medicine (2016)
81. The Role of Toll-Like Receptors in B-Cell Development and Immunopathogenesis of Common Variable Immunodeficiency, Expert Review of Clinical Immunology (2016)
82. A Five Years Study of Tuberculous Meningitis in Iran, Iranian Journal of Pathology (2015)
83. Altered Expression of Micrornas Following Chronic Allograft Dysfunction With Interstitial Fibrosis and Tubular Atrophy, Iranian Journal of Allergy# Asthma and Immunology (2015)
84. Altered Suppressor Function of Regulatory T Cells in Type 1 Diabetes, Iranian Journal of Immunology (2015)
85. Association Between Single Nucleotide Polymorphisms of the Interleukin-4 Gene and Atopic Dermatitis, Acta Dermatovenerologica Croatica (2015)
86. Association of Hla Class Ii (Drb1, Dqa1, Dqb1) Alleles and Haplotypes With Myasthenia Gravis and Its Subgroups in the Iranian Population, Journal of the Neurological Sciences (2015)
87. Association of Hla Class Ii Alleles With Hepatitis C Virus Clearance and Persistence in Thalassemia Patients From Iran, Journal of Medical Virology (2015)
88. Association of Programmed Cell Death 1 and Programmed Cell Death 1 Ligand Gene Polymorphisms With Delayed Graft Function and Acute Rejection in Kidney Allograft Recipients, Iranian Journal of Kidney Diseases (2015)
89. Association Study of Interleukin-1 Family and Interleukin-6 Gene Single Nucleotide Polymorphisms in Recurrent Aphthous Stomatitis, International Journal of Immunogenetics (2015)
90. Differential Expression of Micrornas in Renal Transplant Patients With Acute T-Cell Mediated Rejection, Transplant Immunology (2015)
91. Frequency of Seropositivity Against Infectious Agents Amongst Pemphigus Vulgaris Patients: A Case-Control Study on Strongyloides Stercoralis, Helicobacter Pylori, Toxoplasma Gondii, Leishmania Major, and Epstein-Barr Virus, International Journal of Dermatology (2015)
92. Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology, Immunological Investigations (2015)
93. Granulocyte Colony-Stimulating Factor for Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study of Iranian Patients, Journal of Clinical Neurology (Korea) (2015)
94. Hla-Drb and Hla-Dq Genetic Variability in Patients With Aspirin-Exacerbated Respiratory Disease, American Journal of Rhinology and Allergy (2015)
95. Igg Anti-Iga Antibodies in Paediatric Antibody-Deficient Patients Receiving Intravenous Immunoglobulin, Allergologia et immunopathologia (2015)
96. Il-1A Rs1800587, Il-1B Rs1143634 and Il-1R1 Rs2234650 Polymorphisms in Iranian Patients With Systemic Sclerosis, International Journal of Immunogenetics (2015)
97. Interaction of Bordetella Pertussis Filamentous Hemagglutinin With Human Tlr2: Identification of the Tlr2-Binding Domain, APMIS (2015)
98. Pharmacogenetic Tests to Predict the Efficacy of Aspirin Desensitization in Patients With Aspirin-Exacerbated Respiratory Diseases; Hla-Dqb302, Expert Review of Respiratory Medicine (2015)
99. Pre- and Posttransplant Iga Anti-Fab Antibodies to Predict Long-Term Kidney Graft Survival, Transplantation Proceedings (2015)
100. Rad50 Single-Nucleotide Polymorphism in Predominantly Antibody Deficiency, Journal of Investigational Allergology and Clinical Immunology (2015)
101. Simmunogenetics of Cancer, Cancer Immunology: A Translational Medicine Context (2015)
102. Soluble Major Histocompatibility Complex Class I Chainrelated Antigen a Level in Chronic Allograft Dysfunction, Iranian Journal of Kidney Diseases (2015)