Interferon Regulatory Factors: Where to Stand in Transplantation

Interferon Regulatory Factors: Where to Stand in Transplantation Publisher Pubmed

Assadiasl S¹ ; Shahi A² ; Salehi S² ; Afzali S² ; Amirzargar A^{1, 2}

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1. Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Transplant Immunology Published:2018

Abstract

Interferon regulatory factors (IRFs) are implicated in regulating inflammatory responses to pathogens and alloantigens. Since transplantation is usually accompanied by ischemia reperfusion injury (IRI), acute and chronic rejections, as well as immunodeficiency due to immunosuppressive drugs, IRFs seem to play a considerable role in allograft outcome. For instance, IRF-1 has been shown to be involved in pathogenesis of IRI; however, IRF-2 exhibits an opposite function. Some IRF-3 and 5 SNPs are associated with better or worse graft survival rates. Of note, IRF-4 inhibition has resulted in improved transplant outcomes. Herein we review available studies about IRFs influence on various stages of transplantation. © 2018 Elsevier B.V.

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Style	Citing Format
MLA	Assadiasl S, et al.. "Interferon Regulatory Factors: Where to Stand in Transplantation." Transplant Immunology, vol. 51, no. , 2018, pp. 76-80.
APA	Assadiasl S, Shahi A, Salehi S, Afzali S, Amirzargar A (2018). Interferon Regulatory Factors: Where to Stand in Transplantation. Transplant Immunology, 51(), 76-80.
Chicago	Assadiasl S, Shahi A, Salehi S, Afzali S, Amirzargar A. "Interferon Regulatory Factors: Where to Stand in Transplantation." Transplant Immunology 51, no. (2018): 76-80.
Harvard	Assadiasl S et al. (2018) 'Interferon Regulatory Factors: Where to Stand in Transplantation', Transplant Immunology, 51(), pp. 76-80.
Vancouver	Assadiasl S, Shahi A, Salehi S, Afzali S, Amirzargar A. Interferon Regulatory Factors: Where to Stand in Transplantation. Transplant Immunology. 2018;51():76-80.
BibTex	@article{ author = {Assadiasl S and Shahi A and Salehi S and Afzali S and Amirzargar A}, title = {Interferon Regulatory Factors: Where to Stand in Transplantation}, journal = {Transplant Immunology}, volume = {51}, number = {}, pages = {76-80}, year = {2018} }
RIS	TY - JOUR AU - Assadiasl S AU - Shahi A AU - Salehi S AU - Afzali S AU - Amirzargar A TI - Interferon Regulatory Factors: Where to Stand in Transplantation JO - Transplant Immunology VL - 51 IS - SP - 76 EP - 80 PY - 2018 ER -

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