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Bone Mineral Density and Muscle Mass in Adults With Developmental Skeletal Discrepancies Publisher Pubmed



Sharifi R1 ; Kordi S2 ; Noravesh F3 ; Aghababaei Y4 ; Ramezani M5 ; Maghbooli Z6
Authors
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Authors Affiliations
  1. 1. Oral and Maxillofacial Surgery Department, Craniomaxillofacial Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Oral and Maxillofacial Surgery Department, Dentistry School, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Oral and Maxillofacial Surgery Department, Dental Branch, Craniomaxillofacial Research Center, Tehran Islamic Azad University of Medical Sciences, Tehran, Iran
  4. 4. Faculty Dentistry School, Valencia University, Valencia, Spain
  5. 5. Baqiyatallah University of Medical Sciences, Tehran, Iran
  6. 6. Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: BMC Musculoskeletal Disorders Published:2022


Abstract

Background: It was aimed to investigate the musculoskeletal status in individuals diagnosed with skeletal discrepancies. Methods: This case–control study was performed on 35 patients with developmental skeletal discrepancies listed for orthognathic surgery as a case group and 33 patients who were nominated for wisdom tooth removal as a control group. All participants were aged 18–40 years and the research was carried out in the period between May 2018 and May 2019. Dual X-ray absorptiometry (DEXA) was used to assess bone mass density at three bone sites: total hip, femoral neck, and the spinal lumbar vertebrae (L1-L4). The appendicular muscle mass index (ASMI) was measured based on the four limbs from the DEXA scan. Results: Our data showed that 45.7% (16) of the case group were osteopenic or osteoporotic while in the control group only 21.2% (7) were osteopenic in at least one region (total hip, femoral neck, or lumbar) (p-value = 0.03). Regarding muscle mass, there was significantly lower SMI in subjects with skeletal discrepancies (case group) compared with the control group (median (IQR) 5.9 (2.5) vs. 6.8 (2.9) (kg/m2), respectively, p = 0.04). Conclusions: There is an essential need for more studies to understand the exact interrelationship between musculoskeletal status and skeletal jaw discrepancies. © 2022, The Author(s).