Association Between Dash and Novel Atherogenic Risk Factors, Anthropometric Indices and Foot Ulcer Indicators in Type 2 Diabetic Patients With Foot Ulcer: A Cross-Sectional Study Publisher



Jalalzadeh M^{1, 3} ; Nasliesfahani E² ; Montazer M^{1, 3} ; Geravand F^{1, 3} ; Heidariseyedmahalle M^{1, 3} ; Mahmoodi M⁵ ; Azadbakht L^{1, 2, 4}
Source: Journal of Diabetes and Metabolic Disorders Published:2024

Abstract

Purpose: Diabetes can cause nerve damage, vascular issues, and reduced blood flow to organs such as the feet, leading to foot deformities and ulcers due to high glucose levels. A healthy dietary pattern like DASH can improve insulin sensitivity and weight loss. Due to limited data and rare evidence, our study aims to investigate the relationship between DASH diet adherence and anthropometric, cardiovascular, and foot ulcer indicators. Methods: The study included 339 diabetic patients with foot ulcers (122 females and 217 males). The study gathered data on patient dietary intake, anthropometric measurements, biochemistry, foot ulcers, and novel atherogenic risk factors per international definitions. Results: The average BMI of the participants was 29.2 ± 5.0, 28.1 ± 4.3, and 28.2 ± 4.2 in the tertiles of DASH index (P-value: 0.18). By increasing the adherence to the DASH index, the monofilament score did not change significantly OR: 1.47; CI: (0.81-2.67). Also, foot ulcer area did not change significantly between DASH tertiles OR: 1.01; CI: (0.56-1.83). Atherogenic risk factors also decreased among the DASH tertiles, but statistically not significant. Conclusion: DASH adherence did not change neuropathy score and cholindex and cardiovascular risk factors significantly and has no significant effect on foot ulcer size. © The Author(s), under exclusive licence to Tehran University of Medical Sciences 2024.