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Efficiency of Multispecies Probiotic Supplements in Bioremoval of Bisphenol A: An in Vitro Study Publisher



Solouki S1, 2 ; Fazeli MR3 ; Solouki S1, 2
Authors
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Authors Affiliations
  1. 1. Department of Pharmacology and Toxicology, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran
  2. 2. Department of Biochemistry, National Biochemistry Reference Lab of inherited metabolic disorders, Pasteur Institute, Tehran, Iran
  3. 3. Department of Food and Drug Control, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Biomedical Engineering, School of Electrical and Computer Engineering, University of Tehran, Tehran, Iran

Source: Applied Food Biotechnology Published:2018


Abstract

Background and Objective: Bisphenol A is a well-known industrial compound which is widely used in producing plastic throughout the world. Containers made with these plastics may expose people to small amounts of bisphenol A in food and water and cause adverse effects on human health. In this study, the effect of commercial probiotic formulations on reduction of bisphenol A in aqueous solution is investigated. Material and Methods: One dose of six types of commercial mixtures of probiotic strains were added to a certain amount of bisphenol A in saline basal medium at 37°C. During a 24 h treatment with probiotics, samples were taken from the environments at different times and prepared for further analysis with enzyme-linked immunosorbent assay. The experimental framework was set up in a way that compares formulations and determines the most efficient strains for bisphenol A reduction. In addition, the effect of peripheral conditions such as pH and temperature were also studied. Results and Conclusion: Multi-strain probiotics had an impressively high performance in bio-removal of bisphenol A from aqueous solutions. Up to 80% of bisphenol A concentration was decreased during the first hour of treatment in almost all trials. Among them, the synergy of Lactobacillus acidophilus and Lactobacillus plantarum strains were the most successful. On the other hand, mixture of probiotics had more persistent effect and robust binding ability than single strains. Finally, it can be expected that regular usage of probiotic supplementation with special mixture of strains can suppress the harmful effects of bisphenol A.