Comparative Investigation of Mycotoxin Detoxification Mechanisms by Lactic Acid Bacteria (Lactobacillus Species) and Non-Lactic Acid Bacteria Publisher



Nabgan M¹ ; Shariatifar N¹ ; Zeinali T² Show Affiliations
Source: Journal of Food Measurement and Characterization Published:2025

Abstract

Today, detoxification of mycotoxins has become a challenging issue because of their carcinogenicity, triggering of oxidative stress, and organ dysfunction. Studies have reported the reduction of mycotoxins by bacteria in absorption and degradation. There is a research gap in understanding the detoxification mechanism of mycotoxins by Lactobacillus species, and there is no coherent, precise, or accurate conclusion regarding this. The objective of this study was to conduct an extensive research and compare the mechanism of mycotoxin decontamination by Lactic Acid Bacteria (LAB), especially Lactobacilli, and non-lactic acid bacteria such as Bacillus spp. These findings indicate that lactobacilli can diminish mycotoxins mainly by binding to the cell wall, whereas other bacteria can do so only through enzymatic degradation. Oxidoreductase group enzymes are vital in transforming mycotoxins into safe or less toxic catabolites. Detoxification of mycotoxins by enzymes appears more practical and economical because of mycotoxins’ weak and unstable binding to the bacterial surface. This research provides insights into the practical isolation and use of appropriate bacteria or enzymes to detoxify specific mycotoxins or groups of mycotoxins for industrial applications. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025.