Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment

Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment Publisher

Rezaei M¹ ; Handali S² ; Pourahmad J³

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1. Department of Toxicology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2. Medical Biomaterial Research Center (MBRC), Tehran University of Medical Sciences, Tehran, Iran
3. Department of Pharmacology & Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Mitochondrial Metabolism: An Approach to Disease Management Published:2021

Abstract

Reduction/oxidation-dependent reactions affect many cellular functional pathways. Mitochondria are at the center of these processes, as mitochondria both generate reactive oxygen species (ROS) that drive redox-sensitive events and respond to ROS-mediated changes in the cellular redox state. In this chapter, we discuss the regulation of cellular ROS, their modes of production and removal, and the redox-sensitive targets that are modified by their flux. In particular, we focus on the actions of redox-sensitive targets that change mitochondrial functions. We also consider the role of mitochondria in modulating these events, and discuss how redox-dependent events may contribute to the pathology of diseases by influencing mitochondrial function, particularly the involvement of mitochondrial ROS in diabetes, cancer, and neurodegenerative diseases. © 2021 Elsevier Inc. All rights reserved.

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Style	Citing Format
MLA	Rezaei M, Handali S, Pourahmad J. "Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment." Mitochondrial Metabolism: An Approach to Disease Management, vol. , no. , 2021, pp. 1-17.
APA	Rezaei M, Handali S, Pourahmad J (2021). Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment. Mitochondrial Metabolism: An Approach to Disease Management, (), 1-17.
Chicago	Rezaei M, Handali S, Pourahmad J. "Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment." Mitochondrial Metabolism: An Approach to Disease Management , no. (2021): 1-17.
Harvard	Rezaei M, Handali S, Pourahmad J (2021) 'Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment', Mitochondrial Metabolism: An Approach to Disease Management, (), pp. 1-17.
Vancouver	Rezaei M, Handali S, Pourahmad J. Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment. Mitochondrial Metabolism: An Approach to Disease Management. 2021;():1-17.
BibTex	@article{ author = {Rezaei M and Handali S and Pourahmad J}, title = {Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment}, journal = {Mitochondrial Metabolism: An Approach to Disease Management}, volume = {}, number = {}, pages = {1-17}, year = {2021} }
RIS	TY - JOUR AU - Rezaei M AU - Handali S AU - Pourahmad J TI - Mitochondria As Balancers of Reduction/Oxidation for Intracellular Environment JO - Mitochondrial Metabolism: An Approach to Disease Management VL - IS - SP - 1 EP - 17 PY - 2021 ER -

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