A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent

A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent Publisher

Hosseinjanipirdehi H¹ ; Amigh S² ; Mohajeri A³ ; Nazeri E¹ ; Taheri A¹ ; Majidzadeha K¹ ; Mohammadpour Z⁴ ; Esmaeili R¹

Source: RSC Advances Published:2023

Abstract

In the present study, fluorogenic coumarin-based probes (1-3) through condensation of 4-hydroxy coumarin with malondialdehyde bis(diethyl acetal)/triethyl orthoformate were prepared. The absorption and fluorescence emission properties of 2b and 3 in different solvents were studied, and a considerable solvatochromic effect was observed. The sensitivity of chemosensors 2b and 3 toward various cations and anions was investigated. It was revealed that compound 3 had a distinct selectivity toward Sn2+, possibly via a chelation enhanced quenching mechanism. The fluorescence signal was quenched over the concentration range of 6.6-120 μM, with an LOD value of 3.89 μM. The cytotoxicity evaluation of 3 against breast cancer cell lines demonstrated that the chemosensor was nontoxic and could be used successfully in cellular imaging. The probe responded to tin ions not only via fluorescence quenching, but also through colorimetric signal change. The change in optical properties was observed in ambient conditions and inside living cells. © 2023 The Royal Society of Chemistry.

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Style	Citing Format
MLA	Hosseinjanipirdehi H, et al.. "A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent." RSC Advances, vol. 13, no. 15, 2023, pp. 9811-9823.
APA	Hosseinjanipirdehi H, Amigh S, Mohajeri A, Nazeri E, Taheri A, Majidzadeha K, Mohammadpour Z, Esmaeili R (2023). A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent. RSC Advances, 13(15), 9811-9823.
Chicago	Hosseinjanipirdehi H, Amigh S, Mohajeri A, Nazeri E, Taheri A, Majidzadeha K, Mohammadpour Z, Esmaeili R. "A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent." RSC Advances 13, no. 15 (2023): 9811-9823.
Harvard	Hosseinjanipirdehi H et al. (2023) 'A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent', RSC Advances, 13(15), pp. 9811-9823.
Vancouver	Hosseinjanipirdehi H, Amigh S, Mohajeri A, Nazeri E, Taheri A, Majidzadeha K, et al.. A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent. RSC Advances. 2023;13(15):9811-9823.
BibTex	@article{ author = {Hosseinjanipirdehi H and Amigh S and Mohajeri A and Nazeri E and Taheri A and Majidzadeha K and Mohammadpour Z and Esmaeili R}, title = {A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent}, journal = {RSC Advances}, volume = {13}, number = {15}, pages = {9811-9823}, year = {2023} }
RIS	TY - JOUR AU - Hosseinjanipirdehi H AU - Amigh S AU - Mohajeri A AU - Nazeri E AU - Taheri A AU - Majidzadeha K AU - Mohammadpour Z AU - Esmaeili R TI - A Coumarin-Based Fluorescent Chemosensor As a Sn Indicator and a Fluorescent Cellular Imaging Agent JO - RSC Advances VL - 13 IS - 15 SP - 9811 EP - 9823 PY - 2023 ER -

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