Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections

Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections Publisher Pubmed

Izadpanah M¹ ; Khalili H¹ ; Mohammadi M²

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1. Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Comparative Effectiveness Research Published:2016

Abstract

Aim: In this study, safety of two methods of unfractionated heparin administration for venous thromboembolism prophylaxis was compared in critically ill surgical patients. Methods: A total of 50 surgical critically ill patients randomly assigned to either subcutaneous unfractionated heparin 5000 units three-times a day or continuous intravenous infusion; 625 IU/h. During the intensive care unit (ICU) stay, patients' hemodynamic parameters, laboratory tests, symptoms and signs of thrombosis and bleeding were monitored closely. Results: During the patients' follow-up, no episode of bleeding or venous thromboembolism event was recorded. The differences in ICU and hospital stays were not significantly different between the groups. Conclusion: There are limited evidences regarding safety and efficacy of continuous intravenous infusion of unfractionated heparin for thromboprophylaxis. © 2016 Future Medicine Ltd.

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Hossein Khalili (2)

Mostafa Mohammadi (2)

Style	Citing Format
MLA	Izadpanah M, Khalili H, Mohammadi M. "Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections." Journal of Comparative Effectiveness Research, vol. 5, no. 1, 2016, pp. 31-38.
APA	Izadpanah M, Khalili H, Mohammadi M (2016). Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections. Journal of Comparative Effectiveness Research, 5(1), 31-38.
Chicago	Izadpanah M, Khalili H, Mohammadi M. "Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections." Journal of Comparative Effectiveness Research 5, no. 1 (2016): 31-38.
Harvard	Izadpanah M, Khalili H, Mohammadi M (2016) 'Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections', Journal of Comparative Effectiveness Research, 5(1), pp. 31-38.
Vancouver	Izadpanah M, Khalili H, Mohammadi M. Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections. Journal of Comparative Effectiveness Research. 2016;5(1):31-38.
BibTex	@article{ author = {Izadpanah M and Khalili H and Mohammadi M}, title = {Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections}, journal = {Journal of Comparative Effectiveness Research}, volume = {5}, number = {1}, pages = {31-38}, year = {2016} }
RIS	TY - JOUR AU - Izadpanah M AU - Khalili H AU - Mohammadi M TI - Comparing Safety of Heparin As Continuous Intravenous Infusion and Multiple Subcutaneous Injections JO - Journal of Comparative Effectiveness Research VL - 5 IS - 1 SP - 31 EP - 38 PY - 2016 ER -

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