Tehran University of Medical Sciences

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Determining the Recurrence Rate of Premature Ventricular Complexes and Idiopathic Ventricular Tachycardia After Radiofrequency Catheter Ablation With the Help of Designing a Machine-Learning Model Publisher



Mehrabi Nasab E1, 2 ; Sadeghian S1 ; Vasheghani Farahani A1 ; Yamini Sharif A1 ; Masoud Kabir F1 ; Bavanpour Karvane H3 ; Zahedi A4 ; Bozorgi A1
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Source: Regenerative Therapy Published:2024


Abstract

Ventricular arrhythmias increase cardiovascular morbidity and mortality. Recurrent PVCs and IVT are generally considered benign in the absence of structural heart abnormalities. Artificial intelligence is a rapidly growing field. In recent years, medical professionals have shown great interest in the potential use of ML, an integral part of AI, in various disciplines, including diagnostic applications, decision-making, prognostic stratification, and solving complex pathophysiological aspects of diseases from these data at extraordinary complexity, scale, and acquisition rate. The aim of this study was to design an ML model to predict the probability of PVC and IVT recurrence after RF ablation. Data of patients were collected and manipulated using traditional analysis and various artificial intelligence models, namely MLP, Gradient Boosting Machines, Random Forest, and Logistic Regression. Hypertension, male sex, and the use of non-irrigate catheters were associated with less freedom from arrhythmia. All these results were obtained through traditional analytic methods, and according to AI, none of the variables had a clear effect on the recurrence of arrhythmia. Each AI model presents unique strengths and weaknesses, and further optimization and fine-tuning of these models are necessary to increase their clinical utility. By expanding the dataset, improved predictions can be fostered to ultimately increase the clinical utility of AI in predicting PVC erosion outcomes. © 2024 The Japanese Society for Regenerative Medicine
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