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Clinical and Dermatoscopic Characteristics of Lichen Planus-Like Keratosis in a West-Asian Population Publisher Pubmed



Ansari MS1 ; Akay BN2 ; Cengiz FP3 ; Rosendahl N4 ; Mahmoudi H1 ; Daneshpazhooh M1 ; Rosendahl C5, 6
Authors
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Authors Affiliations
  1. 1. Department of Dermatology, Autoimmune Bullous Diseases Research Center, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Medicine Faculty, Department of Dermatology, Ankara University, Ankara, Turkey
  3. 3. Department of Dermatology, Bezmialem Vakif University, Istanbul, Turkey
  4. 4. Faculty of Science, School of Biomedical Sciences, The University of Queensland, St Lucia, Australia
  5. 5. Primary Care Clinical Unit, Faculty of Medicine, The University of Queensland, Herston, Australia
  6. 6. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Australasian Journal of Dermatology Published:2021


Abstract

Background/Objective: The clinical and dermatoscopic features of lichen planus-like keratosis have been described but the characteristics of this entity in a West-Asian population are not known. Methods: We retrospectively analysed 82 histopathologically verified cases of lichen planus-like keratosis from 81 patients from Iran and Turkey. Results: The majority of lichen planus-like keratoses were macules (61% n = 50), clinically pigmented (67.1% n = 55) and dermatoscopically multi-coloured (91.5% n = 75). The majority (63.4%) had a single dermatoscopic pattern, most frequently: structureless (35.4%), dots (14.6%) and angulated lines (8.5%). Of the lesions with more than one pattern (n = 30), the majority (n = 21) had asymmetry of pattern, the most common combinations being structureless plus dots (n = 8) and structureless plus angulated lines (n = 5). The most common structure was pigmented dots, most frequently grey and present in 70.7% of cases. Vessels were seen in 30.5% of lesions, being significantly more prevalent in non-pigmented, than pigmented, lichen planus-like keratoses (83.3% vs. 21.4% P < 0.001). When we compared lichen planus-like keratosis in the current study to that entity in a large North American study, the statistically significant differences in a West-Asian population included a greater frequency of pigmented variants, a lower incidence in females and a lower prevalence on the torso, in favour of the face. Conclusions: Lichen planus-like keratosis in a West-Asian population has clinical and dermatoscopic similarities to that entity in another studied population. The significant differences in gender association and anatomical site may be secondary to cultural factors. © 2020 The Australasian College of Dermatologists
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