Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin

Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin Publisher Pubmed

Sinz C¹ ; Tschandl P¹ ; Rosendahl C^{2, 3} ; Akay BN⁴ ; Argenziano G⁵ ; Blum A⁶ ; Braun RP⁷ ; Cabo H⁸ ; Gourhant JY⁹ ; Kreusch J¹⁰ ; Lallas A¹¹ ; Lapins J¹² ; Marghoob AA¹³ ; Menzies SW¹⁴ Show All Authors

Sinz C¹
Tschandl P¹
Rosendahl C^{2, 3}
Akay BN⁴
Argenziano G⁵
Blum A⁶
Braun RP⁷
Cabo H⁸
Gourhant JY⁹
Kreusch J¹⁰
Lallas A¹¹
Lapins J¹²
Marghoob AA¹³
Menzies SW¹⁴
Paoli J¹⁵
Rabinovitz HS¹⁶
Rinner C¹⁷
Scope A¹⁸
Soyer HP¹⁹
Thomas L²⁰
Zalaudek I²¹
Kittler H¹

Show Affiliations

1. Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria
2. Faculty of Medicine, The University of Queensland, Brisbane, Australia
3. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Dermatology, Ankara University Faculty of Medicine, Ankara, Turkey
5. Dermatology Unit, University of Campania, Naples, Italy
6. Public Private and Teaching Practice of Dermatology, Konstanz, Germany
7. Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
8. Department of Dermatology, Instituto de Investigaciones Medicas â€œA. Lanari, â€� University of Buenos Aires, Buenos Aires, Argentina
9. Centre de Dermatologie, Nemours, France
10. Private Dermatology Practice, Lubeck, Germany
11. First Department of Dermatology, Aristotle University, Thessaloniki, Greece
12. Department of Dermatology, Karolinska University Hospital, Stockholm, Sweden
13. Memorial Sloan Kettering Cancer Center, Hauppauge, New York, United States
14. Sydney Melanoma Diagnostic Centre, Royal Prince Alfred Hospital and Discipline of Dermatology, University of Sydney, Sydney, Australia
15. Department of Dermatology and Venereology, Sahlgrenska University Hospital, Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
16. Skin and Cancer Associates, Plantation, Florida, United States
17. Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria
18. Department of Dermatology, Chaim Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
19. Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia
20. Department of Dermatology, Centre Hospitalier Lyon Sud, Lyon 1 University, Lyons Cancer Research Center, Lyon, France
21. Department of Dermatology, Medical University of Graz, Graz, Austria

Source: Journal of the American Academy of Dermatology Published:2017

Abstract

Background Nonpigmented skin cancer is common, and diagnosis with the unaided eye is error prone. Objective To investigate whether dermatoscopy improves the diagnostic accuracy for nonpigmented (amelanotic) cutaneous neoplasms. Methods We collected a sample of 2072 benign and malignant neoplastic lesions and inflammatory conditions and presented close-up images taken with and without dermatoscopy to 95 examiners with different levels of experience. Results The area under the curve was significantly higher with than without dermatoscopy (0.68 vs 0.64, P <.001). Among 51 possible diagnoses, the correct diagnosis was selected in 33.1% of cases with and 26.4% of cases without dermatoscopy (P <.001). For experts, the frequencies of correct specific diagnoses of a malignant lesion improved from 40.2% without to 51.3% with dermatoscopy. For all malignant neoplasms combined, the frequencies of appropriate management strategies increased from 78.1% without to 82.5% with dermatoscopy. Limitations The study deviated from a real-life clinical setting and was potentially affected by verification and selection bias. Conclusions Dermatoscopy improves the diagnosis and management of nonpigmented skin cancer and should be used as an adjunct to examination with the unaided eye. © 2017 American Academy of Dermatology, Inc.

2. Expert-Level Diagnosis of Nonpigmented Skin Cancer by Combined Convolutional Neural Networks, JAMA Dermatology (2019)

3. A Prospective Diagnostic Study on Povidone–Iodine Retention in Lesions Suspected to Be Squamous Cell Carcinoma or Keratoacanthoma, Australasian Journal of Dermatology (2019)

4. Dermoscopy Features of Atypical Fibroxanthoma: A Multicenter Study of the International Dermoscopy Society, Australasian Journal of Dermatology (2018)

5. Clinical and Dermatoscopic Characteristics of Lichen Planus-Like Keratosis in a West-Asian Population, Australasian Journal of Dermatology (2021)

6. Can Dermoscopy Open a New Way to Diagnosing Merkel Cell Carcinoma?, International Journal of Dermatology (2019)

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Style	Citing Format
MLA	Sinz C, et al.. "Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin." Journal of the American Academy of Dermatology, vol. 77, no. 6, 2017, pp. 1100-1109.
APA	Sinz C, Tschandl P, Rosendahl C, Akay BN, Argenziano G, Blum A, Braun RP, Cabo H, Gourhant JY, Kreusch J, Lallas A, Lapins J, Marghoob AA, Menzies SW, Paoli J, Rabinovitz HS, Rinner C, Scope A, Soyer HP, ... Kittler H (2017). Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin. Journal of the American Academy of Dermatology, 77(6), 1100-1109.
Chicago	Sinz C, Tschandl P, Rosendahl C, Akay BN, Argenziano G, Blum A, Braun RP, et al.. "Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin." Journal of the American Academy of Dermatology 77, no. 6 (2017): 1100-1109.
Harvard	Sinz C et al. (2017) 'Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin', Journal of the American Academy of Dermatology, 77(6), pp. 1100-1109.
Vancouver	Sinz C, Tschandl P, Rosendahl C, Akay BN, Argenziano G, Blum A, et al.. Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin. Journal of the American Academy of Dermatology. 2017;77(6):1100-1109.
BibTex	@article{ author = {Sinz C and Tschandl P and Rosendahl C and Akay BN and Argenziano G and Blum A and Braun RP and Cabo H and Gourhant JY and Kreusch J and Lallas A and Lapins J and Marghoob AA and Menzies SW and Paoli J and Rabinovitz HS and Rinner C and Scope A and Soyer HP and Thomas L and Zalaudek I and Kittler H}, title = {Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin}, journal = {Journal of the American Academy of Dermatology}, volume = {77}, number = {6}, pages = {1100-1109}, year = {2017} }
RIS	TY - JOUR AU - Sinz C AU - Tschandl P AU - Rosendahl C AU - Akay BN AU - Argenziano G AU - Blum A AU - Braun RP AU - Cabo H AU - Gourhant JY AU - Kreusch J AU - Lallas A AU - Lapins J AU - Marghoob AA AU - Menzies SW AU - Paoli J AU - Rabinovitz HS AU - Rinner C AU - Scope A AU - Soyer HP AU - Thomas L AU - Zalaudek I AU - Kittler H TI - Accuracy of Dermatoscopy for the Diagnosis of Nonpigmented Cancers of the Skin JO - Journal of the American Academy of Dermatology VL - 77 IS - 6 SP - 1100 EP - 1109 PY - 2017 ER -

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