Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray

Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray Publisher Pubmed

Hanafi A¹ ; Kamali M¹ ; Darvishi MH¹ ; Amani A^{2, 3}

Show Affiliations

1. Nanobiotechology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
2. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
3. Medical Biomaterials Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Archives of Razi Institute Published:2018

Abstract

Nowadays, electrospray is becoming a favourable approach for preparing monodispersed nanoparticles. However, this approach is quite recent and requires further works to optimize control over physicochemical properties of its products. This study aimed to determine the possible effects of sonication as a pretreatment to reduce the size of azelaic acid-chitosan particle before using electrospray. The results showed that sonication treatment can produce submicron particles of azelaic acid-chitosan. By diluting the solution and increasing sonication time and amplitude, smaller particles were obtained with the smallest one at 516 nm, sized by dynamic light scattering. The pretreated solution was then electrosprayed to reduce the size of nanoparticles to 80 nm, indicating that sonication may play an important role in reducing the size of electrosprayed nanoparticles. The electrosprayed nanoparticles were nearly monodispersed and almost spherical in shape. © 2018 by Razi Vaccine & Serum Research Institute.

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Mohammad Ali Faramarzi (3)

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Style	Citing Format
MLA	Hanafi A, et al.. "Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray." Archives of Razi Institute, vol. 73, no. 1, 2018, pp. 53-59.
APA	Hanafi A, Kamali M, Darvishi MH, Amani A (2018). Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray. Archives of Razi Institute, 73(1), 53-59.
Chicago	Hanafi A, Kamali M, Darvishi MH, Amani A. "Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray." Archives of Razi Institute 73, no. 1 (2018): 53-59.
Harvard	Hanafi A et al. (2018) 'Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray', Archives of Razi Institute, 73(1), pp. 53-59.
Vancouver	Hanafi A, Kamali M, Darvishi MH, Amani A. Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray. Archives of Razi Institute. 2018;73(1):53-59.
BibTex	@article{ author = {Hanafi A and Kamali M and Darvishi MH and Amani A}, title = {Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray}, journal = {Archives of Razi Institute}, volume = {73}, number = {1}, pages = {53-59}, year = {2018} }
RIS	TY - JOUR AU - Hanafi A AU - Kamali M AU - Darvishi MH AU - Amani A TI - Pretreatment With Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray JO - Archives of Razi Institute VL - 73 IS - 1 SP - 53 EP - 59 PY - 2018 ER -

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