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Immunology of Cutaneous Tumors and Immunotherapy for Melanoma Publisher



Saghazadeh A1, 3 ; Saghazadeh M1, 3 ; Rezaei N1, 2, 3, 4
Authors
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Authors Affiliations
  1. 1. Department of Immunology, Molecular Immunology Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran, 14194, Iran
  2. 2. Research Center for Immuno deficiencies, Children’s Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, 14194, Iran
  3. 3. Department of Immunology, Molecular Immunology Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran, 14194, Iran
  4. 4. Universal Scientific, Education and Research Network (USERN), Tehran, Iran

Source: Cancer Immunology: Cancer Immunotherapy for Organ-Specific Tumors Published:2015


Abstract

This chapter starts with an introduction to the epidemiology of skin cancers and skin immune system. Then, the role of tumor immunity, immunosuppression, and inflammation in skin carcinogenesis would be discussed. This is followed by a brief discussion on photo immunology due to UV radiation which is known as an important risk factor of skin cancers. This chapter starts with an introduction to the epidemiology of skin cancers and skin immune system. Then, the role of tumor immunity, immunosuppression, and inflammation in skin carcinogenesis would be discussed. This is followed by a brief discussion on photoimmunology due to UV radiation which is known as an important risk factor of skin cancers. The last part of this chapter has risen to challenge the immunotherapeutic approaches for melanomas. © Springer-Verlag Berlin Heidelberg 2015.
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