Benchmark Dose

Benchmark Dose Publisher

Noruzi M¹ ; Rezvanfar MA¹ ; Daghighi SM¹

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1. Faculty of Pharmacy, Pharmaceutical Sciences Research Center (PSRC), Tehran University of Medical Sciences (TUMS), Tehran, Iran

Source: Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 Published:2023

Abstract

As an alternative to the standard no observed adverse effect level (NOAEL)/lowest observed adverse effect level (LOAEL) technique, benchmark dose (BMD) modeling has been recommended as a starting point for determining acceptable exposure limits for risk assessment. Regression analysis of the response against dose is used to estimate a BMD by identifying a response level of interest and then determining the dose that resulted in that extent of change. In addition to the BMD estimate, the BMDL (lower confidence limit) is typically determined using this method. There are also different software programs for calculating BMD, like BMDS, PROAST, Bayesian BMD, and MADr-BMD. © 2024 Elsevier Inc. All rights reserved.

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1. 0Uncertainty Factors, Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 (2023)

Style	Citing Format
MLA	Noruzi M, Rezvanfar MA, Daghighi SM. "Benchmark Dose." Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, vol. 1, no. , 2023, pp. V1-939.
APA	Noruzi M, Rezvanfar MA, Daghighi SM (2023). Benchmark Dose. Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, 1(), V1-939.
Chicago	Noruzi M, Rezvanfar MA, Daghighi SM. "Benchmark Dose." Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 1, no. (2023): V1-939.
Harvard	Noruzi M, Rezvanfar MA, Daghighi SM (2023) 'Benchmark Dose', Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, 1(), pp. V1-939.
Vancouver	Noruzi M, Rezvanfar MA, Daghighi SM. Benchmark Dose. Encyclopedia of Toxicology# Fourth Edition: Volume 1-9. 2023;1():V1-939.
BibTex	@article{ author = {Noruzi M and Rezvanfar MA and Daghighi SM}, title = {Benchmark Dose}, journal = {Encyclopedia of Toxicology# Fourth Edition: Volume 1-9}, volume = {1}, number = {}, pages = {V1-939}, year = {2023} }
RIS	TY - JOUR AU - Noruzi M AU - Rezvanfar MA AU - Daghighi SM TI - Benchmark Dose JO - Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 VL - 1 IS - SP - V1 EP - 939 PY - 2023 ER -

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