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A Case of Covid-19-Associated Rhino-Orbito-Cerebral Mucormycosis Caused by Apophysomyces Variabilis With a Review of the Literature Publisher Pubmed



Erami M1, 2 ; Mirhendi H3, 4 ; Momenheravi M2 ; Hezaveh SJH1 ; Ahsaniarani AH5 ; Sabet SS6 ; Aboutalebian S3, 4
Authors
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Authors Affiliations
  1. 1. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Infectious Disease Research Center, Kashan University of Medical Sciences, Kashan, Iran
  3. 3. Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Mycology Reference Laboratory, Research Core Facilities Laboratory, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department Otorhinolaryngology, School of Medicine, Matini Hospital, Kashan University of Medical Sciences, Kashan, Iran
  6. 6. Department of Pharmaceutical, Kashan University of Medical Sciences, Kashan, Iran

Source: Frontiers in Cellular and Infection Microbiology Published:2022


Abstract

A fatal case of COVID-19-associated mucormycosis (CAM) affected a 40-year-old woman who was initially admitted to our hospital due to a SARS-CoV-2 infection. Her clinical condition worsened, and she finally died because of respiratory failure, hemodynamic instability, and mucormycosis with invasion into the orbit and probably the brain. According to DNA sequence analysis of the fungus isolated from the patient, Apophysomyces variabilis was involved. This is the first published case of CAM and the third case of mucormycosis due to this mold. Copyright © 2022 Erami, Mirhendi, Momen-Heravi, Hezaveh, Ahsaniarani, Sabet and Aboutalebian.
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