Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder

Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder Publisher Pubmed

Mohammadzadeh Honarvar N¹ ; Samadi M¹ ; Seyedi Chimeh M¹ ; Gholami F¹ ; Bahrampour N² ; Jalali M¹ ; Effatpanah M³ ; Yekaninejad MS⁴ ; Abdolahi M¹ ; Chamari M¹

Show Affiliations

1. Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Nutrition, Science and Research Branch Islamic Azad University (SRBIAU), Tehran, Iran
3. School of Medicine, Ziaeian Hospital, Tehran University of Medical Sciences, International Campus, Tehran, Iran
4. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Science, Tehran, Iran

Source: International journal of clinical practice Published:2022

Abstract

Method: In this double-blind, randomized, placebo-controlled trial, 75 children (aged 6-12) diagnosed with ADHD were randomly assigned into two groups. The supplementation group received vitamin D3 (2000 IU), and the control group received a placebo for 3 months. Blood samples were collected at baseline and after intervention to analyze the 25(OH)D, paraxonase-1 activity (PON-1), Total Antioxidant Capacity (TAC), and 8-isoprostan levels. Results: A significant rise in circulating 25(OH)D was observed in the vitamin D group versus the placebo group at the end of the study. There was no reduction in 8-isoprostan levels in the vitamin D group compared to the placebo group. Serum paraxonase-1 and TAC concentration decreased in both groups, but these alterations were not statistically significant in the treatment group versus the placebo group at the end of the intervention. Conclusion: Vitamin D supplementation for 3 months did not have beneficial effects on biomarkers of oxidative stress status. To confirm these findings, further studies on children are suggested. Copyright © 2022 Niyaz Mohammadzadeh Honarvar et al.

Style	Citing Format
MLA	Mohammadzadeh Honarvar N, et al.. "Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder." International journal of clinical practice, vol. 2022, no. , 2022, pp. 4836731-.
APA	Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, Effatpanah M, Yekaninejad MS, Abdolahi M, Chamari M (2022). Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder. International journal of clinical practice, 2022(), 4836731-.
Chicago	Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, Effatpanah M, Yekaninejad MS, Abdolahi M, Chamari M. "Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder." International journal of clinical practice 2022, no. (2022): 4836731-.
Harvard	Mohammadzadeh Honarvar N et al. (2022) 'Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder', International journal of clinical practice, 2022(), pp. 4836731-.
Vancouver	Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, et al.. Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder. International journal of clinical practice. 2022;2022():4836731-.
BibTex	@article{ author = {Mohammadzadeh Honarvar N and Samadi M and Seyedi Chimeh M and Gholami F and Bahrampour N and Jalali M and Effatpanah M and Yekaninejad MS and Abdolahi M and Chamari M}, title = {Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder}, journal = {International journal of clinical practice}, volume = {2022}, number = {}, pages = {4836731-}, year = {2022} }
RIS	TY - JOUR AU - Mohammadzadeh Honarvar N AU - Samadi M AU - Seyedi Chimeh M AU - Gholami F AU - Bahrampour N AU - Jalali M AU - Effatpanah M AU - Yekaninejad MS AU - Abdolahi M AU - Chamari M TI - Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder JO - International journal of clinical practice VL - 2022 IS - SP - 4836731 EP - PY - 2022 ER -

Style

Citing Format

MLA

Mohammadzadeh Honarvar N, et al.. "Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder." International journal of clinical practice, vol. 2022, no. , 2022, pp. 4836731-.

APA

Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, Effatpanah M, Yekaninejad MS, Abdolahi M, Chamari M (2022). Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder. International journal of clinical practice, 2022(), 4836731-.

Chicago

Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, Effatpanah M, Yekaninejad MS, Abdolahi M, Chamari M. "Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder." International journal of clinical practice 2022, no. (2022): 4836731-.

Harvard

Mohammadzadeh Honarvar N et al. (2022) 'Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder', International journal of clinical practice, 2022(), pp. 4836731-.

Vancouver

Mohammadzadeh Honarvar N, Samadi M, Seyedi Chimeh M, Gholami F, Bahrampour N, Jalali M, et al.. Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder. International journal of clinical practice. 2022;2022():4836731-.

BibTex

@article{ author = {Mohammadzadeh Honarvar N and Samadi M and Seyedi Chimeh M and Gholami F and Bahrampour N and Jalali M and Effatpanah M and Yekaninejad MS and Abdolahi M and Chamari M}, title = {Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder}, journal = {International journal of clinical practice}, volume = {2022}, number = {}, pages = {4836731-}, year = {2022} }

RIS

TY - JOUR
AU - Mohammadzadeh Honarvar N
AU - Samadi M
AU - Seyedi Chimeh M
AU - Gholami F
AU - Bahrampour N
AU - Jalali M
AU - Effatpanah M
AU - Yekaninejad MS
AU - Abdolahi M
AU - Chamari M
TI - Effect of Vitamin D on Paraxonase-1, Total Antioxidant Capacity, and 8-Isoprostan in Children With Attention Deficit Hyperactivity Disorder
JO - International journal of clinical practice
VL - 2022
IS -
SP - 4836731
EP -
PY - 2022
ER -

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Abstract